about
P688
Inhibition of adipogenesis by Wnt signalingInhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding proteinThe role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt responseMechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradationRegulation of the Wnt signaling pathway by disabled-2 (Dab2)Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactorDirect inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signalingA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorAxin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Tankyrase inhibition stabilizes axin and antagonizes Wnt signallingAxin negatively affects tau phosphorylation by glycogen synthase kinase 3betaMutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's diseaseA beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aidaWnt signaling through inhibition of β-catenin degradation in an intact Axin1 complexSUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stabilityDomains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localizationControl of beta-catenin phosphorylation/degradation by a dual-kinase mechanismTGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesisPutative tumor suppressor EDD interacts with and up-regulates APCLow-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathwayFrizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signalingAxin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activationThe mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formationIdentification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domainBoth the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesisDab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactionsDelayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycinInteraction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-cateninGeneration of Axin1 conditional mutant miceA case of neighboring loci with similar effectsFunctional domains of axin. Importance of the C terminus as an oligomerization domainA divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubulesN-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formationAxin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formationTransgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmissionAxin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functionsA role for Wnt signalling in self-renewal of haematopoietic stem cells
P921
Q22254771-F172A7BF-A3F6-4EFF-946F-88EF859DAD49Q24290612-EBE61662-D612-4823-8874-7D2490C116EEQ24295277-A1334AA3-028C-4014-B660-FAD47E2D9EE5Q24296778-F06CDA59-D5C1-4BEC-8743-84F36683456AQ24299975-77D227B5-BA43-4773-8DE7-9948E2428CC3Q24301873-11E48E23-B837-4BD4-A302-95C0C66B459CQ24305113-CD7D4D70-5353-4C46-AC3B-C454DCF2CC4DQ24305619-F5F6AFA5-D292-4D20-9D11-66BD1078990AQ24310506-1E14C2E5-97DC-465F-960E-5F1B4E028EECQ24313393-AA31A4F8-DBBC-40E3-9C59-3670E2CD037BQ24315751-44BE71A4-B36C-498E-8E7C-7B4BBACAF749Q24316697-3C410987-0DA6-4966-B758-A3C77C2E6D52Q24317033-6358D316-673C-4400-9DD5-BFDA745ABBC6Q24317702-2EDE6036-10FA-439E-8256-EF7B113BACF2Q24336491-C0D374DD-EBC9-42BD-BF77-67B52CF55D4AQ24337717-35954F37-2F40-4288-84A9-A6CD313DAF0BQ24647790-0B0F5BEE-31B6-4CB5-9A8D-79CC49A551ECQ24682053-6D12A2A5-1D01-4300-8FAF-CD3D88A5D6BEQ28114789-AC568B10-AA92-4A1F-A8B9-9B2A0444948EQ28114976-5AEA3ED0-FDA8-425F-AB69-4B831F2451AFQ28115427-40E20055-E688-4264-AF46-EE871691FA30Q28118992-84ECB32D-7466-4B21-839B-9F9F2130808BQ28119021-5193D889-FD83-4E7F-8029-9F89A9C1E899Q28189206-876C7C49-7F42-4749-BB63-C7BF3129A79FQ28244304-E8503485-06E6-44E1-A6FF-1D4F17CDBCF8Q28295415-716A16D3-D637-47B1-AA8F-14F16749B63BQ28506899-1F61E548-B3B2-41D2-819F-6729DCCE5695Q28507287-4797727E-C29F-453F-B863-AA69645A41EDQ28507393-03EADEC9-FEFF-4B19-847D-DECFD5845C02Q28509243-C55CBD30-FEAA-4A64-A1D1-6795380CC47EQ28509692-2ECEA3D8-F940-4782-9213-FB1B190D581FQ28511054-2FE5A1BC-640F-4D74-A4A3-386CFA1F9B08Q28511175-0DC7E4C6-B862-499C-B0A8-7E0CEEAAB7E6Q28511342-851B7092-8A48-4FA1-931A-0E2DFF0217B7Q28586223-EE3099FB-C059-440F-839B-7F73F3DE0838Q28586879-BF5B7015-7FCB-43C7-B133-33C97BFF97CDQ28587574-15504041-85E5-44CF-9485-87CEFADB688CQ28588249-F69CAC7C-A986-40E5-B45D-A12B40FBAF92Q28591541-6A25C7BA-B647-4650-B0A6-31755FB7C5B7Q28592213-383092DF-95B1-4007-9E38-46577B22F96B
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Axin 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Axin 1
@en
type
label
Axin 1
@en
altLabel
Axin1
@en
axin-1
@en
axis inhibition protein 1
@en
protein Fused
@en
prefLabel
Axin 1
@en
P361
P527
P637
P680
P681
P682
P705
P352
P638
P31
P352
P361
P637
NP_001153070
XP_006523578
XP_006523579
XP_030105311
XP_030105312
P680
P681
P682
P702
P703
P705
ENSMUSP00000073974
ENSMUSP00000113756
ENSMUSP00000127182
ENSMUSP00000132000