A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation - Test2 - elhamkhani - TriplyDB

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

http://www.wikidata.org/entity/Q24652200

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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB OTULIN restricts Met1-linked ubiquitination to control innate immune signaling Activation of interferon regulatory factor 5 by site specific phosphorylation ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development Function of Nod-like receptors in microbial recognition and host defense NOD-like receptors (NLRs): bona fide intracellular microbial sensors Ubiquitin signaling in immune responses Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis NF-κB, the first quarter-century: remarkable progress and outstanding questions Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation The role of ubiquitylation in immune defence and pathogen evasion Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases NOD-Like Receptors: Master Regulators of Inflammation and Cancer The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells RIP2 activity in inflammatory disease and implications for novel therapeutics Regulation of inflammatory and antiviral signaling by A20.Nod2: A Critical Regulator of Ileal Microbiota and Crohn's Disease CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling NLRs, inflammasomes, and viral infection Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis Neonatal lethality in knockout mice expressing the kinase-dead form of the gefitinib target GAK is caused by pulmonary dysfunction The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction Therapeutic targeting of NOD1 receptors IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.Dysregulation of p38 and MKP-1 in response to NOD1/TLR4 stimulation in sarcoid bronchoalveolar cells.Activation of the nucleotide oligomerization domain signaling pathway by the non-bacterially derived xanthone drug 5'6-dimethylxanthenone-4-acetic acid (Vadimezan).E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-α stimulation of synovial cells: an in vitro study.NOD-like receptors in intestinal homeostasis and epithelial tissue repair.Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

http://www.wikidata.org/entity/Q24652200

description

2008 nî lūn-bûn

@nan

2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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type

label

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

@en

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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prefLabel

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

@ast

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

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Gabriel Núñez

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Koichi Fukase

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Mizuho Hasegawa

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Naohiro Inohara

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Peter C Lucas

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P2860

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

Reciprocal cross-talk between Nod2 and TAK1 signaling pathways

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

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5768286

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18079694

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2234345

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