CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis
about
Molecular cloning and sequence analysis of hamster CENP-A cDNA.Analysis of mitotic phosphorylation of borealinThe kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignmentPhosphorylation at serine 331 is required for Aurora B activation.Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora BThe GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscissionProteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate.Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresCentromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENPNovel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinaseDeath receptor-induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphaseExploring the functional interactions between Aurora B, INCENP, and survivin in mitosisFunctional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinaseBub1 is essential for assembly of the functional inner centromere.Chromatin Dynamics in Vivo: A Game of Musical ChairsCell division: control of the chromosomal passenger complex in time and spaceExcess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivoDual role of topoisomerase II in centromere resolution and aurora B activityEssential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosisAurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma.A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis.The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassemblyA novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cellsAurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic processCentromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)atedSequential assembly of centromeric proteins in male mouse meiosisRaf kinase inhibitory protein regulates aurora B kinase and the spindle checkpointCdk1, Plks, Auroras, and Neks: the mitotic bodyguardsDe novo kinetochore assembly requires the centromeric histone H3 variant.The cellular geography of aurora kinasesα-amino trimethylation of CENP-A by NRMT is required for full recruitment of the centromereSpatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Posttranslational modification of CENP-A influences the conformation of centromeric chromatin.Epigenetic centromere specification directs aurora B accumulation but is insufficient to efficiently correct mitotic errors.Bod1, a novel kinetochore protein required for chromosome biorientation.Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpointA functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.The histone fold domain of Cse4 is sufficient for CEN targeting and propagation of active centromeres in budding yeast.
P2860
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P2860
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@ast
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@en
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@nl
type
label
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@ast
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@en
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@nl
prefLabel
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@ast
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@en
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@nl
P2860
P921
P3181
P356
P1476
CENP-A is phosphorylated by Au ...... e in completion of cytokinesis
@en
P2093
R D Shelby
S G Zeitlin
P2860
P304
P3181
P356
10.1083/JCB.200108125
P407
P577
2001-12-24T00:00:00Z