Identification of human Rap1: implications for telomere evolution
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityThe human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcriptRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2Rap1 affects the length and heterogeneity of human telomeresPOT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsGenome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityIn vivo stoichiometry of shelterin componentsPOT1 association with TRF2 regulates telomere lengthCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresThe human Rap1 protein complex and modulation of telomere lengthHuman Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicingHuman Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointShelterin complex and associated factors at human telomeresFinding the end: recruitment of telomerase to telomeresCharacterization of the yeast telomere nucleoprotein core: Rap1 binds independently to each recognition siteCENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesisIn vivo veritas: using yeast to probe the biological functions of G-quadruplexesUp-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesisHuman Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubulesOxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage responseTelomere and Telomerase Therapeutics in CancerTelomeres-structure, function, and regulationMultiple facets of TPP1 in telomere maintenanceA shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteinsStructural and Functional Studies of the Rap1 C-Terminus Reveal Novel Separation-of-Function MutantsA conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organismsSLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with TelomeresRap1 prevents telomere fusions by nonhomologous end joining.Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDNA and dsDNA-binding proteins and their target sitesTelomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome endsTRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeresA human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteins
P2860
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P2860
Identification of human Rap1: implications for telomere evolution
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Identification of human Rap1: implications for telomere evolution
@ast
Identification of human Rap1: implications for telomere evolution
@en
Identification of human Rap1: implications for telomere evolution
@en-gb
Identification of human Rap1: implications for telomere evolution
@nl
type
label
Identification of human Rap1: implications for telomere evolution
@ast
Identification of human Rap1: implications for telomere evolution
@en
Identification of human Rap1: implications for telomere evolution
@en-gb
Identification of human Rap1: implications for telomere evolution
@nl
prefLabel
Identification of human Rap1: implications for telomere evolution
@ast
Identification of human Rap1: implications for telomere evolution
@en
Identification of human Rap1: implications for telomere evolution
@en-gb
Identification of human Rap1: implications for telomere evolution
@nl
P3181
P1433
P1476
Identification of human Rap1: implications for telomere evolution
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)80858-2
P407
P577
2000-05-26T00:00:00Z