Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis
about
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocksDifferential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen speciesThe adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memoryMammalian Cdh1/Fzr mediates its own degradationRegulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycleCENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesisUSP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of ClaspinCdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteinsNuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylationConserved C-terminal domains of mCenp-F (LEK1) regulate subcellular localization and mitotic checkpoint delayMouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysisThe anaphase promoting complex/cyclosome: a machine designed to destroyThe APC/C inhibitor, Emi1, is essential for prevention of rereplicationCyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).Atypical E2F activity restrains APC/CCCS52A2 function obligatory for endocycle onsetSIAMESE cooperates with the CDH1-like protein CCS52A1 to establish endoreplication in Arabidopsis thaliana trichomes.A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae.Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20pSubstrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complexOncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisCyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells.The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition.Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.E2F activity is essential for survival of Myc-overexpressing human cancer cells.The anaphase promoting complex induces substrate degradation during neuronal differentiation.ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stressAPC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.Synchronization of interphase events depends neither on mitosis nor on cdk1
P2860
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P2860
Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@ast
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@en
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@nl
type
label
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@ast
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@en
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@nl
prefLabel
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@ast
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@en
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@nl
P2093
P2860
P50
P1476
Nonperiodic activity of the hu ...... nthesis uncoupled from mitosis
@en
P2093
C S Sorensen
E R Kramer
J M Peters
P2860
P304
P356
10.1128/MCB.20.20.7613-7623.2000
P407
P577
2000-10-01T00:00:00Z