Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
about
The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts.Convergence of vitamin D and retinoic acid signalling at a common hormone response element.Silencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinomaAntitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cellsInhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signalingE2F1 induces p19INK4d, a protein involved in the DNA damage response, following UV irradiationIsolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicityCAK-independent activation of CDK6 by a viral cyclinRegulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1)Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitorsp53-independent functions of the p19(ARF) tumor suppressorMesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3The ankyrin repeat as molecular architecture for protein recognitionTransforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsInteraction of D-type cyclins with a novel myb-like transcription factor, DMP1Id2 specifically alters regulation of the cell cycle by tumor suppressor proteinsIdentification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2BThe role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cellsTargeting CDK6 in cancer: State of the art and new insightsStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activityStructure of the cyclin-dependent kinase inhibitor p19Ink4dGenetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae.Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesisThe INK4 family of cell cycle inhibitors in cancerRegulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleusGankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasomeEvidence of a role for the INK4 family of cyclin-dependent kinase inhibitors in ovarian granulosa cell tumorsIdentification of CDK4 sequences involved in cyclin D1 and p16 bindingGene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanismBiochemical characterization of p16INK4- and p18-containing complexes in human cell linesAn important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferationThe expression pattern of the cell cycle inhibitor p19(INK4d) by progenitor cells of the rat embryonic telencephalon and neonatal anterior subventricular zoneRedistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiationEffects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationMolecular cloning and characterization of the human p19INK4dgene promoterIdentification of genes periodically expressed in the human cell cycle and their expression in tumorsRole of p19ink4d in the pathogenesis of hearing loss.
P2860
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P248
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P2860
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@ast
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@en
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@nl
type
label
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@ast
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@en
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@nl
prefLabel
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@ast
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@en
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@nl
P2093
P2860
P921
P3181
P356
P1476
Novel INK4 proteins, p19 and p ...... ependent kinases CDK4 and CDK6
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.15.5.2672
P407
P577
1995-05-01T00:00:00Z