Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
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Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progressionAntitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cellsInhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signalingCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsIdentification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint geneIsolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4Cyclin-binding motifs are essential for the function of p21CIP1Growth suppression by p16ink4 requires functional retinoblastoma proteinMenin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsArrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcriptionCyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivoCAK-independent activation of CDK6 by a viral cyclinThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsInteraction of D-type cyclins with a novel myb-like transcription factor, DMP1Id2 specifically alters regulation of the cell cycle by tumor suppressor proteinsRegulation of p16CDKN2 expression and its implications for cell immortalization and senescenceIdentification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6Human cyclin E, a nuclear protein essential for the G1-to-S phase transitionTumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR dataCyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidizationStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activityAn essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiaeDistinct versus redundant properties among members of the INK4 family of cyclin-dependent kinase inhibitorsA cyclin D-Cdk4 activity required for G2 phase cell cycle progression is inhibited in ultraviolet radiation-induced G2 phase delayThe INK4 family of cell cycle inhibitors in cancerRegulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleusEvidence of a role for the INK4 family of cyclin-dependent kinase inhibitors in ovarian granulosa cell tumorsGene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanismBiochemical characterization of p16INK4- and p18-containing complexes in human cell linesBoth p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinaseAn important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferationRedistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiationCloning and expression of cDNA encoding rat liver 60-kDa lysophospholipase containing an asparaginase-like region and ankyrin repeatTranscriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanismEffects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationCyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylationRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes
P2860
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P2860
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Growth suppression by p18, a p ...... es with wild-type pRb function
@ast
Growth suppression by p18, a p ...... es with wild-type pRb function
@en
Growth suppression by p18, a p ...... es with wild-type pRb function
@en-gb
Growth suppression by p18, a p ...... es with wild-type pRb function
@nl
type
label
Growth suppression by p18, a p ...... es with wild-type pRb function
@ast
Growth suppression by p18, a p ...... es with wild-type pRb function
@en
Growth suppression by p18, a p ...... es with wild-type pRb function
@en-gb
Growth suppression by p18, a p ...... es with wild-type pRb function
@nl
prefLabel
Growth suppression by p18, a p ...... es with wild-type pRb function
@ast
Growth suppression by p18, a p ...... es with wild-type pRb function
@en
Growth suppression by p18, a p ...... es with wild-type pRb function
@en-gb
Growth suppression by p18, a p ...... es with wild-type pRb function
@nl
P2093
P3181
P356
P1433
P1476
Growth suppression by p18, a p ...... es with wild-type pRb function
@en
P2093
C L O'Keefe
C W Jenkins
M A Nichols
P304
P3181
P356
10.1101/GAD.8.24.2939
P407
P577
1994-12-01T00:00:00Z