Compound Management for Quantitative High-Throughput Screening
about
High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationshipsThe Tox21 robotic platform for the assessment of environmental chemicals--from vision to realityIdentification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatBQuantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase InhibitorsFirefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a ReporterTitration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase InhibitorsIdentification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of actionIdentification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1High-throughput 1,536-well fluorescence polarization assays for α(1)-acid glycoprotein and human serum albumin bindingDiverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collectionA panel of diverse assays to interrogate the interaction between glucokinase and glucokinase regulatory protein, two vital proteins in human diseaseMethod for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase α in Quantitative High-Throughput Screening (qHTS) Bioluminescent FormatCurrent approaches for the discovery of drugs that deter substance and drug abuse.Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory siteIdentification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity.Paradigm shift in toxicity testing and modeling.Monitoring of HTS compound library quality via a high-resolution image acquisition and processing instrument.Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol proteaseA high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.A robotic platform for quantitative high-throughput screeningIdentification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assayA basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolutionMonitoring compound integrity with cytochrome P450 assays and qHTS.Advances in improving the quality and flexibility of compound management.High-quality cost-effective compound management support for HTS.A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical librariesThe pilot phase of the NIH Chemical Genomics Center.Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.Identification of small molecule compounds that inhibit the HIF-1 signaling pathwayComparison of bioluminescent kinase assays using substrate depletion and product formation.A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity.A miniaturized screen for inhibitors of Jumonji histone demethylases.A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase.Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assayA multiplex calcium assay for identification of GPCR agonists and antagonists.An automated approach to efficiently reformat a large collection of compounds.The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurementsA homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.
P2860
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P2860
Compound Management for Quantitative High-Throughput Screening
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Compound Management for Quantitative High-Throughput Screening
@ast
Compound Management for Quantitative High-Throughput Screening
@en
Compound Management for Quantitative High-Throughput Screening
@nl
type
label
Compound Management for Quantitative High-Throughput Screening
@ast
Compound Management for Quantitative High-Throughput Screening
@en
Compound Management for Quantitative High-Throughput Screening
@nl
prefLabel
Compound Management for Quantitative High-Throughput Screening
@ast
Compound Management for Quantitative High-Throughput Screening
@en
Compound Management for Quantitative High-Throughput Screening
@nl
P2093
P2860
P50
P1476
Compound Management for Quantitative High-Throughput Screening
@en
P2093
Douglas Auld
James Inglese
Paul Shinn
Sam Michael
P2860
P356
10.1016/J.JALA.2007.12.004
P407
P577
2008-04-01T00:00:00Z