c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
about
BRCTx is a novel, highly conserved RAD18-interacting proteinPUMA, a potent killer with or without p53JNK signalling in cancer: in need of new, smarter therapeutic targetsTherapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesQuantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4The circadian clock in cancer development and therapyChk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibitionp53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARCDeregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitorsFunctional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesisRNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells.Myc is required for activation of the ATM-dependent checkpoints in response to DNA damagePUMA decreases the growth of prostate cancer PC-3 cells independent of p53.Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients.Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice.Inflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells.Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.GP130 activation induces myeloma and collaborates with MYC.BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis.Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.Connecting proliferation and apoptosis in development and disease.Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformationBH3-only proteins in cell death initiation, malignant disease and anticancer therapy.Cutting edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cellsSelection against PUMA gene expression in Myc-driven B-cell lymphomagenesis.Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA.Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex.Apoptotic signaling by c-MYC.Hypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide.Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinasesDirect repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro.c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.Nfkb 1 is dispensable for Myc-induced lymphomagenesis.Myc: the beauty and the beast.
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P2860
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@ast
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@en
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@nl
type
label
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@ast
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@en
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@nl
prefLabel
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@ast
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@en
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@nl
P2093
P2860
P921
P3181
P1476
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL
@en
P2093
Carlos Rodriguez-Galindo
John L Cleveland
Jonas A Nilsson
Kirsteen H Maclean
Ulrich B Keller
P2860
P304
P3181
P356
10.1128/MCB.23.20.7256-7270.2003
P407
P577
2003-10-01T00:00:00Z