Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
about
Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactionsBcl-G, a novel pro-apoptotic member of the Bcl-2 familyInvolvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infectionThe molecular mechanism of Noxa-induced mitochondrial dysfunction in p53-mediated cell deathNoxa is necessary for hydrogen peroxide-induced caspase-dependent cell deathAATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosisNoxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsGlioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressorExpression of the Bcl-3 proto-oncogene suppresses p53 activationEndoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alphaDifferential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathwaysp53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosisPUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cellsDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineagesThe interferon stimulated gene 54 promotes apoptosisBOK and NOXA are essential mediators of p53-dependent apoptosisHzf Determines cell survival upon genotoxic stress by modulating p53 transactivationHIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic functionPBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.Localization of dynein light chains 1 and 2 and their pro-apoptotic ligandsThe bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53.SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencingThe p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinaseExpression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signalsHIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levelsGeneral transcriptional coactivator PC4 activates p53 functionAlterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XLWISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinaseA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathDRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosisNew insights into the role of nuclear factor-kB in cell growth regulationApoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesUltraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin AgingCellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization
P2860
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P2860
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@ast
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@en
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@nl
type
label
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@ast
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@en
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@nl
prefLabel
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@ast
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@en
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@nl
P2093
P3181
P1433
P1476
Noxa, a BH3-only member of the ...... iator of p53-induced apoptosis
@en
P2093
T Taniguchi
T Yamashita
P304
P3181
P356
10.1126/SCIENCE.288.5468.1053
P407
P50
P577
2000-05-01T00:00:00Z