Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer
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Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1Clinicopathologic significance of TRAP1 expression in colorectal cancer: a large scale study of human colorectal adenocarcinoma tissuesPhase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancerTRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC.Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cellsCombination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicityPreclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancerSignaling the mitochondrial unfolded protein response.Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics.Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancerMitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila.Heat shock proteins in breast cancer progression--a suitable case for treatment?TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive FormIdentifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach.Correlation between mitochondrial TRAP-1 expression and lymph node metastasis in colorectal cancerRole of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -a study of the OVCAD consortiumAberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer.Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasisOxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.Combination of TRAP1 and ERCC1 Expression Predicts Clinical Outcomes in Metastatic Colorectal Cancer Treated with Oxaliplatin/5-Fluorouracil.Tumour markers in prostate cancer II: diagnostic and prognostic cellular biomarkers.TRAP-1, the mitochondrial Hsp90.New insights into TRAP1 pathway.The mitochondrial permeability transition pore and its adaptive responses in tumor cells.Organelle-specific Hsp90 inhibitors.TRAP1: a viable therapeutic target for future cancer treatments?Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development.Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells.The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines.TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins.Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1.TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors2.4 Å resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.High mitochondria content is associated with prostate cancer disease progressionHeat shock protein 90 (hsp90) expression and breast cancer.
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Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@ast
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@en
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@nl
type
label
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@ast
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@en
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@nl
prefLabel
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@ast
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@en
Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@nl
P2093
P2860
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Cytoprotective mitochondrial c ...... and metastatic prostate cancer
@en
P2093
Dario C Altieri
Hira Lal Goel
Irwin Leav
Janet Plescia
Ronald J Cohen
Zhong Jiang
P2860
P304
P3181
P356
10.2353/AJPATH.2010.090521
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P577
2010-01-01T00:00:00Z