The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system - Test2 - elhamkhani - TriplyDB

The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

http://www.wikidata.org/entity/Q24655164

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Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system A role for brain stress systems in addiction.Dynorphin, stress, and depression Repeated swim stress induces kappa opioid-mediated activation of extracellular signal-regulated kinase 1/2 Clinical potential of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome A Possible Role of Anhedonia as Common Substrate for Depression and Anxiety Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction Role of kappa-opioid receptors in stress and anxiety-related behavior.Neuropeptide modulation of central amygdala neuroplasticity is a key mediator of alcohol dependence.Drug withdrawal conceptualized as a stressor.Stress and VTA synapses: implications for addiction and depression Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain.Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety.Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit Neurobiology of aversive states.A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System Kappa Opioids, Salvinorin A and Major Depressive Disorder Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus Effect of chronic ethanol on enkephalin in the hypothalamus and extra-hypothalamic areas CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior Repeated stress exposure causes strain-dependent shifts in the behavioral economics of cocaine in rats κ Agonists as a novel therapy for menopausal hot flashes.Direct targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitry Central effects of ethanol interact with endogenous mu-opioid activity to control isolation-induced analgesia in maternally separated infant rats.Protracted manifestations of acute dependence after a single morphine exposure.μ-Opioid blockade reduces ethanol effects on intake and behavior of the infant rat during short-term but not long-term social isolation.Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the κ-opioid receptor antagonist JDTic.Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse.Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat.Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone.

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P2860

The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

http://www.wikidata.org/entity/Q24655164

description

2008 nî lūn-bûn

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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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type

label

The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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The dysphoric component of str ...... dynorphin kappa-opioid system

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JNEUROSCI.4458-07.2008

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Journal of Neuroscience

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The dysphoric component of str ...... dynorphin kappa-opioid system

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Benjamin B Land

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Charles Chavkin

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Erica J Melief

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Julia C Lemos

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Mei Xu

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Michael R Bruchas

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P2860

Stress, dysregulation of drug reward pathways, and the transition to drug dependence

Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.

Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase

Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses

Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system

Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes

Depression: a new animal model sensitive to antidepressant treatments

Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats

Psychotomimesis mediated by kappa opiate receptors

The mesolimbic dopamine reward circuit in depression

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10.1523/JNEUROSCI.4458-07.2008

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2

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2008-01-09T00:00:00Z

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18184783

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2612708

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