Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system
about
Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid systemDynorphin, stress, and depressionRepeated swim stress induces kappa opioid-mediated activation of extracellular signal-regulated kinase 1/2The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid systemStress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.Kappa-opioid ligands in the study and treatment of mood disorders15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuseDynorphin--still an extraordinarily potent opioid peptideRole of kappa-opioid receptors in stress and anxiety-related behavior.Drug withdrawal conceptualized as a stressor.Emotional valence and context of social influences on drug abuse-related behavior in animal models of social stress and prosocial interactionKappa Opioids, Salvinorin A and Major Depressive DisorderEndogenous opiates and behavior: 2006Fear and the Defense Cascade: Clinical Implications and Management.Affective cue-induced escalation of alcohol self-administration and increased 22-kHz ultrasonic vocalizations during alcohol withdrawal: role of kappa-opioid receptors.Individual differences and social influences on the neurobehavioral pharmacology of abused drugs.Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the κ-opioid receptor antagonist JDTic.Molecular and genetic substrates linking stress and addictionHigh-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains.Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.Presynaptic inhibition of diverse afferents to the locus ceruleus by kappa-opiate receptors: a novel mechanism for regulating the central norepinephrine systemLoss of environmental enrichment increases vulnerability to cocaine addiction.The development and maintenance of drug addictionAntidepressant-like effects of kappa-opioid receptor antagonists in Wistar Kyoto rats.Synergistic antidepressant-like effects between a kappa opioid antagonist (LY2444296) and a delta opioid agonist (ADL5859) in the mouse forced swim test.Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and femalesEffectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-inducedEffects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice.The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuseBehavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanismsAnimal models of depression: molecular perspectives.Systems genetics of the lateral septal nucleus in mouse: heritability, genetic control, and covariation with behavioral and morphological traits.Effects of buprenorphine on behavioral tests for antidepressant and anxiolytic drugs in miceEffects of a post-shock injection of the kappa opioid receptor antagonist norbinaltorphimine (norBNI) on fear and anxiety in rats.Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats.A role for the mu opioid receptor in the antidepressant effects of buprenorphine.The kappa opioid receptor: from addiction to depression, and back.Large scale expression changes of genes related to neuronal signaling and developmental processes found in lateral septum of postpartum outbred mice.Opioid partial agonist buprenorphine dampens responses to psychosocial stress in humansKappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats.
P2860
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P2860
Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Social defeat stress-induced b ...... endogenous kappa opioid system
@ast
Social defeat stress-induced b ...... endogenous kappa opioid system
@en
Social defeat stress-induced b ...... endogenous kappa opioid system
@nl
type
label
Social defeat stress-induced b ...... endogenous kappa opioid system
@ast
Social defeat stress-induced b ...... endogenous kappa opioid system
@en
Social defeat stress-induced b ...... endogenous kappa opioid system
@nl
prefLabel
Social defeat stress-induced b ...... endogenous kappa opioid system
@ast
Social defeat stress-induced b ...... endogenous kappa opioid system
@en
Social defeat stress-induced b ...... endogenous kappa opioid system
@nl
P2093
P2860
P356
P1476
Social defeat stress-induced b ...... endogenous kappa opioid system
@en
P2093
Charles Chavkin
Jay P McLaughlin
Joseph Valdez
Theodore A Chavkin
P2860
P2888
P304
P356
10.1038/SJ.NPP.1300872
P407
P577
2006-06-01T00:00:00Z
P5875
P6179
1036295273