Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users - Test2 - elhamkhani - TriplyDB

Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users

Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users

http://www.wikidata.org/entity/Q24644973

about

Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors.Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys.Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence Molecular and genetic substrates linking stress and addiction Differential roles of ventral pallidum subregions during cocaine self-administration behaviors Does the difference between physically active and couch potato lie in the dopamine system?Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse Rapid phasic activity of ventral pallidal neurons during cocaine self-administration Sex differences in kappa opioid pharmacology Targeting the dopamine D3 receptor: an overview of drug design strategies.Fluoxetine potentiation of methylphenidate-induced gene regulation in striatal output pathways: potential role for 5-HT1B receptor Exploring drug-target interaction networks of illicit drugs.Life-long consequences of juvenile exposure to psychotropic drugs on brain and behavior.Serum proteomic analysis reveals high frequency of haptoglobin deficiency and elevated thyroxine level in heroin addicts.The endogenous opioid system in cocaine addiction: what lessons have opioid peptide and receptor knockout mice taught us?Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons.A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals.Higher binding of the dopamine D3 receptor-preferring ligand [11C]-(+)-propyl-hexahydro-naphtho-oxazin in methamphetamine polydrug users: a positron emission tomography study.Ventral pallidum roles in reward and motivation.Cocaine use reduction with buprenorphine (CURB): rationale, design, and methodology.Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine.kappa-Opioid receptor signaling and brain reward function The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.Orquestic regulation of neurotransmitters on reward-seeking behavior.Does the kappa opioid receptor system contribute to pain aversion?Insights from Preclinical Choice Models on Treating Drug Addiction.Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs.Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics.Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine

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P2860

Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users

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2008 nî lūn-bûn

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2008年の論文

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Striatal and ventral pallidum ...... in human chronic cocaine users

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J.NEUROPHARM.2008.04.019

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Neuropharmacology

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Striatal and ventral pallidum ...... in human chronic cocaine users

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Glen R Hanson

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Lloyd Bush

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Mario E Alburges

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Paul S Frankel

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Stephen J Kish

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P2860

The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans

Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum

A new anatomical framework for neuropsychiatric disorders and drug abuse

The effects of naltrexone on alcohol and cocaine use in dually addicted patients

The neural basis of addiction: a pathology of motivation and choice

Regional distribution of cocaine in postmortem brain of chronic human cocaine users.

Contrasting responses by basal ganglia met-enkephalin systems to low and high doses of methamphetamine in a rat model.

Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits.

Synaptic plasticity in drug reward circuitry.

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corpus striatum

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