In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
about
Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation.Characterization of the intramolecular G-quadruplex promoting activity of Est1.Unwinding the functions of the Pif1 family helicases.Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4)."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteinsA G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Suppression of gene expression by G-quadruplexes in open reading frames depends on G-quadruplex stability.Unfolding mechanism of thrombin-binding aptamer revealed by molecular dynamics simulation and Markov State Model.Telomeres do the (un)twist: helicase actions at chromosome termini.Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase.Application of metal coordination chemistry to explore and manipulate cell biology.Genome-wide colonization of gene regulatory elements by G4 DNA motifsTelomerase is essential to alleviate pif1-induced replication stress at telomeres.Arc1p: anchoring, routing, coordinating.Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potentialPotential in vivo roles of nucleic acid triple-helices.DNA structural properties in the classification of genomic transcription regulation elements.Stability and bioactivity of thrombin binding aptamers modified with D-/L-isothymidine in the loop regions.Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer.Analysis of aptamer sequence activity relationships.Seven essential questions on G-quadruplexes.The molecular mechanism of ligand unbinding from the human telomeric G-quadruplex by steered molecular dynamics and umbrella sampling simulations.Irregular G-quadruplexes Found in the Untranslated Regions of Human mRNAs Influence Translation.Strong preference of BRCA1 protein to topologically constrained non-B DNA structures.Investigation of the interactions between methylene blue and intramolecular G-quadruplexes: an explicit distinction in electrochemical behavior.Chromosome positioning and the clustering of functionally related loci in yeast is driven by chromosomal interactions.Molecular mechanisms by which oxidative DNA damage promotes telomerase activity.G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPE
P2860
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P2860
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@ast
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@en
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@nl
type
label
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@ast
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@en
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@nl
prefLabel
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@ast
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@en
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@nl
P2093
P2860
P3181
P1433
P1476
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes
@en
P2093
F Brad Johnson
Jasmine S Smith
Jay E Johnson
Marina L Kozak
P2860
P304
P3181
P356
10.1016/J.BIOCHI.2008.02.013
P407
P577
2008-08-01T00:00:00Z