Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
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The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex componentsThe MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repairLoss of pRB causes centromere dysfunction and chromosomal instabilityGenome stability is ensured by temporal control of kinetochore-microtubule dynamicsCornelia de Lange syndrome, cohesin, and beyondMolecular origins of cancer: Molecular basis of colorectal cancerWhen 2+2=5: the origins and fates of aneuploid and tetraploid cellsSequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesSynthetic lethality and cancer: cohesin and PARP at the replication forkThe ancient and evolving roles of cohesin in gene expression and DNA repairGenetic and epigenetic traits as biomarkers in colorectal cancerCohesin mutations in myeloid malignancies: underlying mechanismsProteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair.Genetics of colorectal cancerCohesin: functions beyond sister chromatid cohesionCohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomesAn evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic developmentAgo1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cellsProtein quantitative trait loci identify novel candidates modulating cellular response to chemotherapyA novel multiplexed, image-based approach to detect phenotypes that underlie chromosome instability in human cellsKnocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cellsMutant Cohesin in Premature Ovarian FailureSomatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypesStudies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesionGeneration of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesisCohesion fatigue induces chromatid separation in cells delayed at metaphase.Whole chromosome gain does not in itself confer cancer-like chromosomal instabilityDefective sister chromatid cohesion is synthetically lethal with impaired APC/C function.Characterization of chromosomal instability in murine colitis-associated colorectal cancer.YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplificationSpectrum and consequences of SMC1A mutations: the unexpected involvement of a core component of cohesin in human disease.Defining the blueprint of the cancer genome.Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells.Targeted sister chromatid cohesion by Sir2.One-hit wonders of genomic instability.Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms.Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved.Genome-wide DNA methylation analysis in cohesin mutant human cell lines.
P2860
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P2860
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Chromatid cohesion defects may ...... ty in human colorectal cancers
@ast
Chromatid cohesion defects may ...... ty in human colorectal cancers
@en
Chromatid cohesion defects may ...... ty in human colorectal cancers
@nl
type
label
Chromatid cohesion defects may ...... ty in human colorectal cancers
@ast
Chromatid cohesion defects may ...... ty in human colorectal cancers
@en
Chromatid cohesion defects may ...... ty in human colorectal cancers
@nl
prefLabel
Chromatid cohesion defects may ...... ty in human colorectal cancers
@ast
Chromatid cohesion defects may ...... ty in human colorectal cancers
@en
Chromatid cohesion defects may ...... ty in human colorectal cancers
@nl
P2093
P2860
P50
P356
P1476
Chromatid cohesion defects may ...... ty in human colorectal cancers
@en
P2093
Forrest Spencer
Giovanni Parmigiani
Irene Barrett
Karen W Y Yuen
Sanford Markowitz
Thomas D Barber
Yasaman Nouhi
P2860
P304
P356
10.1073/PNAS.0712384105
P407
P50
P577
2008-03-04T00:00:00Z