Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
about
Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregationCLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelityThe CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cellsLoss of pRB causes centromere dysfunction and chromosomal instabilityNuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitorChromosomal instability and cancer: a complex relationship with therapeutic potentialRegulation of localization and activity of the microtubule depolymerase MCAKTowards a quantitative understanding of mitotic spindle assembly and mechanicsRegulation of kinetochore-microtubule attachments through homeostatic control during mitosisPhosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cellsChromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubulesLateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKKinesins to the core: The role of microtubule-based motor proteins in building the mitotic spindle midzoneBCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisThe causes and consequences of genetic heterogeneity in cancer evolutionA mechanism linking extra centrosomes to chromosomal instabilityThe mitotic origin of chromosomal instability.Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement.Mechanisms of chromosome behaviour during mitosisTemporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis.Chromosome size in diploid eukaryotic species centers on the average length with a conserved boundary.Kif18B interacts with EB1 and controls astral microtubule length during mitosis.Rapid microtubule self-assembly kineticsPolo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance.Pericentromere tension is self-regulated by spindle structure in metaphase.Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation.Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochoresInositol Pyrophosphate Kinase Asp1 Modulates Chromosome Segregation Fidelity and Spindle Function in Schizosaccharomyces pombe.Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity.MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochoreMCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cellsOverexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.
P2860
Q21558513-D388A19B-AF59-40CD-BA7B-6ADD9B8AFAA6Q24300214-601009EC-CA01-48E2-8073-E2F39DC6AA0FQ24305557-05E1FBC5-6850-47B9-BAF0-3E6395071EEEQ24321598-19859805-E51C-42A1-A57E-A572C40C5848Q24338466-BB8F0856-6711-4A53-9B20-413AADAF0541Q24608609-71BFDA08-B98A-429E-93B2-7404E5265BD4Q24614530-35AA57C7-4715-4298-BB14-5975F57DD2D6Q24633928-EEB6B73A-3F11-46CC-BD43-E15BCAC5922DQ26866233-FC9554C8-5FA3-49A6-A1B8-963E178D21B3Q27321639-C7692114-1796-42EF-9513-777CE2CA51A0Q27345177-F7007FE0-875A-4FCA-A5A6-5080482A23EAQ28115312-7B856CA7-9715-4CFA-B45D-C08894511226Q28118830-6DF7D3DA-6F93-4873-BC81-7AFED0CF0CB9Q28271618-F7CBC166-3ECD-4581-9CA0-1708AB76D18FQ28468367-AF4E0E05-560B-4D7B-992B-81250E78F604Q28550165-8919284B-A2E9-4D72-88BE-DFD4E363FE87Q29615848-E31698AE-30CF-45BD-9911-356C0F5FBF80Q29617923-402F6EFA-FF31-40D9-9488-0F8FF62AFA21Q30408039-A0740D5C-215B-4D2E-B934-4B3CCD0DE243Q30491189-7C294F22-DB30-43ED-9218-DE0B6C5278E8Q30491665-6EE36F94-D49B-4CBF-B06C-B17703CCE9B1Q30495185-7332D1E9-316D-4529-B959-2C33396F1929Q30498045-69FF43E9-FDD9-45EB-ABEC-0CBBA7DA27E7Q30500341-032EF189-511A-4C79-9618-19D52BD9326EQ30503862-A32BE89F-00F9-47F4-BD36-7E203E9A9809Q30504124-9DDD344F-D88C-42C0-A09D-2E89EF6F5616Q30528929-48FB685D-75D2-43B1-8A6D-F005D12C2FECQ30529809-177FC6C9-7827-4461-9E15-93E899BFF75EQ30559683-70658B97-F562-4A2B-8FF9-D623BFEC286DQ30577907-B860D597-3A98-497B-BB32-C0A15294990EQ30579157-4EAE02DD-C1AE-41F2-9D73-59DBC6F8EC8CQ30637438-45132B33-9F1C-4FD1-BE58-370E374E77A6Q30658815-D1523CBE-331C-423A-AA47-E203B61BDACBQ30822375-CAA28F71-D870-45C8-8B6D-AF333B1179A4Q30830013-3C3D5973-9913-48BC-BB3C-85CCC3DE74F5Q30832109-2DEA55F7-4201-410D-BC4A-95B14FD46C85Q33506945-B444C7CA-D6E4-4144-BB04-8084E25BDB1EQ33560603-7FE6CA01-41A3-46B9-B194-433A76F2C5ECQ33587810-6977EE65-B677-439D-A21C-B23A93A6D656Q33616502-CC1A96C8-2A88-4515-B42E-5773D56242AF
P2860
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@ast
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en-gb
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@nl
type
label
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@ast
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en-gb
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@nl
prefLabel
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@ast
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en-gb
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@nl
P2860
P921
P3181
P356
P1433
P1476
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
@en
P2093
Amity L Manning
Sarah L Thompson
P2860
P2888
P3181
P356
10.1038/NCB1809
P407
P577
2008-12-07T00:00:00Z
P5875
P6179
1008762596