Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro - Test2 - elhamkhani - TriplyDB

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

http://www.wikidata.org/entity/Q24669545

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Kinesin-5: cross-bridging mechanism to targeted clinical therapy The mitotic spindle: linking teratogenic effects of Zika virus with human genetics?A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding Pathway of ATP hydrolysis by monomeric kinesin Eg5 Microtubule cross-linking triggers the directional motility of kinesin-5 Force and premature binding of ADP can regulate the processivity of individual Eg5 dimers Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors.Extracting signal from noise: kinetic mechanisms from a Michaelis-Menten-like expression for enzymatic fluctuations TPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule.The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5 Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.Anaphase B Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function The mitotic kinesin CENP-E is a processive transport motor.Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states.Single-headed mode of kinesin-5.Kinesin-5-dependent poleward flux and spindle length control in Drosophila embryo mitosis Kinesin-5 acts as a brake in anaphase spindle elongation.Mitotic kinesin CENP-E promotes microtubule plus-end elongation.Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis.Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells.Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube.Cooperative protofilament switching emerges from inter-motor interference in multiple-motor transport.Kinesin-5 is a microtubule polymerase.Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast.Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular Machines Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics Simulations Cryo-electron tomography of microtubule-kinesin motor complexes Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks.Opposite-polarity motors activate one another to trigger cargo transport in live cells Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope.Mechanism and regulation of kinesin-5, an essential motor for the mitotic spindle.Robust transport by multiple motors with nonlinear force-velocity relations and stochastic load sharing.3D motion of vesicles along microtubules helps them to circumvent obstacles in cells Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14 A mitotic kinesin-6, Pav-KLP, mediates interdependent cortical reorganization and spindle dynamics in Drosophila embryos.

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P2860

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

http://www.wikidata.org/entity/Q24669545

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Individual dimers of the mitot ...... ort substantial loads in vitro

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Nature Cell Biology

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Individual dimers of the mitot ...... ort substantial loads in vitro

@en

P2093

Polly M Fordyce

http://www.w3.org/2001/XMLSchema#string

Susan P Gilbert

http://www.w3.org/2001/XMLSchema#string

Troy C Krzysiak

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P2860

Optical trapping.

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Mitotic spindle organization by a plus-end-directed microtubule motor

A structural change in the kinesin motor protein that drives motility

Simultaneous, coincident optical trapping and single-molecule fluorescence

An automated two-dimensional optical force clamp for single molecule studies.

Biased binding of single molecules and continuous movement of multiple molecules of truncated single-headed kinesin.

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470-6

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scholarly article

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2223557

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10.1038/NCB1394

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5

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8

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Megan T Valentine

Steven M. Block

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2006-05-01T00:00:00Z

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7176000

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1023141135

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16604065

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1523314

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