Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells - Test2 - elhamkhani - TriplyDB

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

http://www.wikidata.org/entity/Q24670084

about

Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells HOXA9 regulates miR-155 in hematopoietic cells MicroRNA-126 regulates HOXA9 by binding to the homeobox Hematopoietic fingerprints: an expression database of stem cells and their progeny A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster Factors and networks that underpin early hematopoiesis Transcription factor-mediated reprogramming toward hematopoietic stem cells Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL SALL4 is a key transcription regulator in normal human hematopoiesis A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis Evidence that the Pim1 kinase gene is a direct target of HOXA9 Cul4A is required for hematopoietic stem-cell engraftment and self-renewal MOZ is essential for maintenance of hematopoietic stem cells Hoxa10 null animals exhibit reduced platelet biogenesis.Comparing anterior and posterior Hox complex formation reveals guidelines for predicting cis-regulatory elements PAFc, a key player in MLL-rearranged leukemogenesis.Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin protein Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors.Temporal changes in Hox gene expression accompany endothelial cell differentiation of embryonic stem cells.Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation MLL becomes functional through intra-molecular interaction not by proteolytic processing Thyroid-specific transcription factors and their roles in thyroid cancer.Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells.Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles.Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.Hypoxic metabolism in human hematopoietic stem cells.Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development.Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.Construction of a High-Density Genetic Map and Quantitative Trait Locus Mapping in the Sea Cucumber Apostichopus japonicus.Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes.Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic stem cell development.Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4 MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.

P2860

Q21144471-91312C9A-1D4B-4460-969A-0C0A0C67CBD3 Q24610579-AD45580B-11D8-4081-956D-E00B2A50F91A Q24646559-1A58131A-4099-49EE-8E7C-3EECEA6E12A6 Q24656674-9470D5CA-E9EC-41F2-B06F-3E6D0FD4D567 Q24657435-E04C43BA-2246-4F1B-A2B6-3FF3847CD4B1 Q27022335-072DE86A-2789-4C73-BDE3-A2D1D9961122 Q27023005-D43DE722-098F-4A14-84AB-F543E108A468 Q28082027-4D1EBCA9-067D-4F32-B72F-3DC8D12F332F Q28086765-CB9901D8-4865-4DA4-A79B-0EAE1B3F56F1 Q28239532-E85598E8-FC82-4EB6-9A30-ACE69D6ABD48 Q28273918-682A9FD1-B07F-47AE-8350-6662A1B1678E Q28298834-6AE45271-C210-40D8-B6FE-CC638ED2EEB8 Q28507053-3ED0E691-FA11-4F85-B727-208FD059C02A Q28587021-33C5ABFD-90F9-42B9-B568-21593C88422B Q28587906-3471178F-FA44-45B0-814C-ED5EACCDDA86 Q33429796-A53AF53E-AB8C-4BAB-92F0-A25412B2A324 Q33912447-0904ECBF-C86E-4698-9EA5-B9F9D20020BB Q34245737-2DB472BE-76BC-4CC8-9B3B-C24BCAD357E9 Q34551218-185B809F-FED7-4628-BC4D-70223B71D25B Q34567472-8D187CE9-1A9C-481A-9E18-CAED6299CF33 Q34891250-A257A340-8415-4FBE-A4AE-DC5F71E244C0 Q34977743-32B5D9D6-B507-484C-8055-520328C79A5C Q34989041-4F14BE92-7034-42F4-8070-935B433AAD41 Q35038884-1806239D-8F74-4705-969E-78AAE753E4B1 Q35041289-34F7EF24-7CFB-4D86-88FC-4F925F3E26BB Q35608150-1AB3BC26-D527-44E4-A821-368B9E461D06 Q35634908-7A94B753-5503-458D-B5C8-28F3B943330C Q35651764-0C214090-4134-418C-AC85-EC6873A799CD Q35653085-CFE4A6C4-B3F5-4742-8CCC-12A16BBA7986 Q35685082-0AE076E4-9DFE-47AF-9483-E292645D7313 Q35688076-80F3B55E-9377-4A8A-924A-E8CE1E0698C6 Q35719929-5D6654FC-9919-4784-A2AE-906E9659E2F8 Q35896780-F60C55C7-D050-4FE6-BFCC-291992D7031B Q36048889-39851695-1E35-4AF3-8E64-565A722C4F70 Q36101066-2274973A-F9D5-44FD-AB29-608182956793 Q36124296-56CD59E7-3C58-4D49-B3A4-873781A7C5D7 Q36392936-50104AEA-0352-4CAE-BBE0-03888B01AA28 Q36426330-5F59C8CB-1F34-4F99-93EA-F4B2AF5A81E6 Q36606972-1D787245-A32F-4699-B21B-E123E29D6E56 Q36618536-543B8C28-7866-4B4E-9F39-2AD4560992B4

P2860

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

http://www.wikidata.org/entity/Q24670084

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

name

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@ast

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@en

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@nl

type

label

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@ast

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@en

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@nl

prefLabel

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@ast

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@en

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@nl

P1433

Q24670084-243F86DC-8D1F-4712-84B4-D32FC7804DD2

P1476

Q24670084-D2EBDC54-62EF-4C12-ADA9-B04DCCC867C4

P2093

Q24670084-081250E8-4FCB-494A-BFE6-7D4D6532E56B

Q24670084-1001B7D0-69D2-4D9D-932B-2A84AC45AE49

Q24670084-6B620C1D-DE67-480E-9589-4D45D9D13879

Q24670084-8A60A412-EB55-4A13-AC26-1BF19F853DEC

Q24670084-B9CC7A33-9D85-4473-A663-8533BDC7033D

Q24670084-BC22CC4F-9623-465A-95EB-A7CB6F2F5824

Q24670084-E2D8F1D6-3DCC-4908-B91E-9943D2C819BA

P2860

Q24670084-004FCDB7-CDEB-4B20-9CD2-4C643229494A

Q24670084-012DBD81-4EFF-4DCD-B6D1-735B0FFCDE73

Q24670084-07294EB7-7311-47B9-8209-D3D6608418AE

Q24670084-0AC02A23-B5F6-4A06-ABBB-F48E29C14F5A

Q24670084-1C6CBFD5-7498-4E64-B05A-983B6B91307E

Q24670084-1F48627F-26D2-4D10-86C5-58C1EA73448D

Q24670084-3641ADEA-22DF-4D79-81E1-E816C90E2D34

Q24670084-3CCC09BC-7CFE-474F-9E73-939811DECE57

Q24670084-464A97E0-9D79-4B8B-B936-BE642476F1BE

Q24670084-48C07091-5A7F-4053-8E5D-AD9E9787DAD7

P304

Q24670084-CE6945D9-F720-4F01-B8A0-E962361F8F10

P31

Q24670084-08285C5F-3B9C-4FAA-8677-97DAD037DF69

P3181

Q24670084-84620B9E-97C5-4CE1-8B0B-93C6A415291A

P356

Q24670084-4FDA7840-0077-4AE5-B8ED-4ADC873FDA46

P407

Q24670084-443B2F72-6730-4AE3-89B2-4CB6EAEF847F

P433

Q24670084-EC073BA0-D0C5-4B52-947E-EF5C7F2E3785

P478

Q24670084-D09F8109-7F9A-4284-B348-23D564B5FFCD

P50

Q24670084-FDB0DD82-B3EC-429E-9586-9C4CB480E159

P577

Q24670084-EA9AE258-7315-4BCA-8F28-7449FBA1B320

P5875

Q24670084-97446CF8-CFE7-4660-A554-DCA5E562A0BE

P698

Q24670084-2C50170C-737B-464B-8CD0-806BDA80E0EC

P921

Q24670084-AA2B6DC5-4AF2-4C3B-BDC2-56DAC6ACC7B6

P932

Q24670084-0AF06631-8469-40CE-90E8-6074D2658924

P3181

P356

BLOOD-2005-05-2003

P1433

P1476

Loss of expression of the Hoxa ...... ty of hematopoietic stem cells

@en

P2093

Corey Largman

http://www.w3.org/2001/XMLSchema#string

Guy Sauvageau

http://www.w3.org/2001/XMLSchema#string

H Jeffrey Lawrence

http://www.w3.org/2001/XMLSchema#string

Irving Weissman

http://www.w3.org/2001/XMLSchema#string

Julie Christensen

http://www.w3.org/2001/XMLSchema#string

Stephen Fong

http://www.w3.org/2001/XMLSchema#string

Yu-Long Hu

http://www.w3.org/2001/XMLSchema#string

P2860

Transcription factor GATA-1 regulates human HOXB2 gene expression in erythroid cells

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells

Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors

Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells

Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions

Osteoblastic cells regulate the haematopoietic stem cell niche

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

P304

3988-3994

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

870183

http://www.w3.org/2001/XMLSchema#string

P356

10.1182/BLOOD-2005-05-2003

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

106

http://www.w3.org/2001/XMLSchema#string

P50

R Keith Humphries

P577

2005-08-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7669801

http://www.w3.org/2001/XMLSchema#string

P698

16091451

http://www.w3.org/2001/XMLSchema#string

P921

P932

1895111

http://www.w3.org/2001/XMLSchema#string