MOZ is essential for maintenance of hematopoietic stem cells
about
The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targetingRoles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formationStructural insights into recognition of acetylated histone ligands by the BRPF1 bromodomainMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesMOZ increases p53 acetylation and premature senescence through its complex formation with PMLRecognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF)MOZ and MORF, two large MYSTic HATs in normal and cancer stem cellsCombinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcriptionRegulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human DiseaseHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyp53 Acetylation: Regulation and ConsequencesHBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic developmentMOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndromeMutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone AcetylationTargeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesisHomozygous disruption of the Tip60 gene causes early embryonic lethality.Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos.Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZCrystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.The MOZ histone acetyltransferase in epigenetic signaling and disease.The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.The chromatin regulator Brpf1 regulates embryo development and cell proliferationBivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2Males absent on the first (MOF): from flies to humans.The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identityChromatin regulatory mechanisms in pluripotency.Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells.Dominant mutations in KAT6A cause intellectual disability with recognizable syndromic features.MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic MechanismsVascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.Epigenetics: judge, jury and executioner of stem cell fate.Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.The MYST family of histone acetyltransferases and their intimate links to cancer.Leukemia and hematopoietic stem cells: balancing proliferation and quiescence.
P2860
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P2860
MOZ is essential for maintenance of hematopoietic stem cells
description
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
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artículu científicu espublizáu en 2006
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im Mai 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/05/15)
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vědecký článek publikovaný v roce 2006
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wetenschappelijk artikel (gepubliceerd op 2006/05/15)
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наукова стаття, опублікована в травні 2006
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مقالة علمية (نشرت في 15-5-2006)
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name
MOZ is essential for maintenance of hematopoietic stem cells
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MOZ is essential for maintenance of hematopoietic stem cells
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MOZ is essential for maintenance of hematopoietic stem cells
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type
label
MOZ is essential for maintenance of hematopoietic stem cells
@ast
MOZ is essential for maintenance of hematopoietic stem cells
@en
MOZ is essential for maintenance of hematopoietic stem cells
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prefLabel
MOZ is essential for maintenance of hematopoietic stem cells
@ast
MOZ is essential for maintenance of hematopoietic stem cells
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MOZ is essential for maintenance of hematopoietic stem cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
MOZ is essential for maintenance of hematopoietic stem cells
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P2093
Atsushi Iwama
Hitoshi Ichikawa
Issay Kitabayashi
Shinobu Ueda
Takahiro Ochiya
Takuo Katsumoto
Yukiko Aikawa
P2860
P304
P3181
P356
10.1101/GAD.1393106
P577
2006-05-15T00:00:00Z