SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
about
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseGenealogy of an ancient protein family: the Sirtuins, a family of disordered membersSirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcriptionChromatin regulation and genome maintenance by mammalian SIRT6SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70Calorie restriction and the exercise of chromatinRedox regulation of FoxO transcription factorsForever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegenerationSirtuin 1 and sirtuin 3: physiological modulators of metabolismTargeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsThe role of mammalian sirtuins in the regulation of metabolism, aging, and longevityCell cycle regulators guide mitochondrial activity in radiation-induced adaptive responseRedox regulation of SIRT1 in inflammation and cellular senescenceSirtuins in epigenetic regulationSirtuin-dependent epigenetic regulation in the maintenance of genome integrityUridine prevents fenofibrate-induced fatty liverThe role of sirtuins in cardiac diseaseFunction of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseThe Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the CochleaDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsp300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammalsSIRT3 and cancer: tumor promoter or suppressor?Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signalingMetformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolismSirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesisBiochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylationMammalian sirtuins: biological insights and disease relevanceA role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasisA new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein.Crosstalk between the DNA damage response, histone modifications and neovascularisation.Functional dissection of SIRT6: identification of domains that regulate histone deacetylase activity and chromatin localizationThe secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoformsNeuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.Surprising sirtuin crosstalk in the heart.Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.Sirt3, mitochondrial ROS, ageing, and carcinogenesis.Mitochondrial-nuclear epistasis: implications for human aging and longevity.Sirtuin catalysis and regulation
P2860
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P2860
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@ast
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@en
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@nl
type
label
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@ast
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@en
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@nl
prefLabel
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@ast
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@en
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@nl
P2860
P3181
P356
P1433
P1476
SirT3 is a nuclear NAD+-depend ...... ochondria upon cellular stress
@en
P2093
Alejandro Vaquero
Michael B Scher
P2860
P3181
P356
10.1101/GAD.1527307
P407
P577
2007-04-15T00:00:00Z