The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement - Test2 - elhamkhani - TriplyDB

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

http://www.wikidata.org/entity/Q24683336

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Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates Human single-stranded DNA binding proteins are essential for maintaining genomic stability Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart Characterization of functional domains in human Claspin The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplication DNA polymerase ε and its roles in genome stability RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response Timeless links replication termination to mitotic kinase activation Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns The Implications of Multiple Circadian Clock Origins Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1 Activation of the ATR kinase by the RPA-binding protein ETAA1 Potential conservation of circadian clock proteins in the phylum Nematoda as revealed by bioinformatic searches Timeless preserves telomere length by promoting efficient DNA replication through human telomeres ATR: an essential regulator of genome integrity SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway Checkpoint independence of most DNA replication origins in fission yeast Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks The annealing helicase HARP protects stalled replication forks HARPing on about the DNA damage response during replication.Identification of SMARCAL1 as a component of the DNA damage response.Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.Replication protein A: directing traffic at the intersection of replication and repair.Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells.Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast.Global analysis of the eukaryotic pathways and networks regulated by Salmonella typhimurium in mouse intestinal infection in vivo.Hypomorphic PCNA mutation underlies a human DNA repair disorder.SMARCAL1 and replication stress: an explanation for SIOD?Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin.

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The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

http://www.wikidata.org/entity/Q24683336

description

2007 nî lūn-bûn

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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

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2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

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2007年论文

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name

The human Tim/Tipin complex co ...... replication fork displacement

@ast

The human Tim/Tipin complex co ...... replication fork displacement

@en

The human Tim/Tipin complex co ...... replication fork displacement

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type

label

The human Tim/Tipin complex co ...... replication fork displacement

@ast

The human Tim/Tipin complex co ...... replication fork displacement

@en

The human Tim/Tipin complex co ...... replication fork displacement

@nl

prefLabel

The human Tim/Tipin complex co ...... replication fork displacement

@ast

The human Tim/Tipin complex co ...... replication fork displacement

@en

The human Tim/Tipin complex co ...... replication fork displacement

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Molecular and Cellular Biology

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The human Tim/Tipin complex co ...... replication fork displacement

@en

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Keziban Unsal-Kaçmaz

http://www.w3.org/2001/XMLSchema#string

Marila Cordeiro-Stone

http://www.w3.org/2001/XMLSchema#string

Parviz Minoo

http://www.w3.org/2001/XMLSchema#string

Paul D Chastain

http://www.w3.org/2001/XMLSchema#string

Ping-Ping Qu

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William K Kaufmann

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P2860

hRAD30 mutations in the variant form of xeroderma pigmentosum

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint

Coupling of human circadian and cell cycles by the timeless protein.

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

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2469256

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10.1128/MCB.02190-06

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8

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27

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17296725

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1899931

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