The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
about
Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesisRNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usageHuR recruits let-7/RISC to repress c-Myc expressionHallmarks of cancer and AU-rich elementsPosttranscriptional regulation of cancer traits by HuRIdentification of a signature motif in target mRNAs of RNA-binding protein AUF1Running on empty: how p53 controls INS/IGF signaling and affects life spanAttenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cellsNovel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.Minireview: posttranscriptional regulation of the insulin and insulin-like growth factor systemsNorthwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.Krüppel -like factor 8 is a stress-responsive transcription factor that regulates expression of HuR.Human T-cell leukemia virus open reading frame II encodes a posttranscriptional repressor that is recruited at the level of transcription.Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway.HuR controls mitochondrial morphology through the regulation of BclxL translation.The human IGF1R IRES likely operates through a Shine-Dalgarno-like interaction with the G961 loop (E-site) of the 18S rRNA and is kinetically modulated by a naturally polymorphic polyU loop.Different modes of interaction by TIAR and HuR with target RNA and DNATranslational control of cytochrome c by RNA-binding proteins TIA-1 and HuRCaspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription.HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironmentApigenin prevents UVB-induced cyclooxygenase 2 expression: coupled mRNA stabilization and translational inhibition.ElrA binding to the 3'UTR of cyclin E1 mRNA requires polyadenylation elements.Sex hormone-dependent attenuation of EAE in a transgenic mouse with astrocytic expression of the RNA regulator HuR.HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells.Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs.RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alphaRNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosisERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanismMKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90.Conserved Non-Coding Sequences are Associated with Rates of mRNA Decay in Arabidopsis.Small molecule inhibitors of IRES-mediated translation.RNA-binding protein HuR interacts with thrombomodulin 5'untranslated region and represses internal ribosome entry site-mediated translation under IL-1 beta treatment.Protecting the stress response, guarding the MKP-1 mRNAPost-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype.Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence.
P2860
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P2860
The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The ELAV RNA-stability factor ...... and IRES-mediated translation
@ast
The ELAV RNA-stability factor ...... and IRES-mediated translation
@en
The ELAV RNA-stability factor ...... and IRES-mediated translation
@nl
type
label
The ELAV RNA-stability factor ...... and IRES-mediated translation
@ast
The ELAV RNA-stability factor ...... and IRES-mediated translation
@en
The ELAV RNA-stability factor ...... and IRES-mediated translation
@nl
prefLabel
The ELAV RNA-stability factor ...... and IRES-mediated translation
@ast
The ELAV RNA-stability factor ...... and IRES-mediated translation
@en
The ELAV RNA-stability factor ...... and IRES-mediated translation
@nl
P2093
P2860
P3181
P356
P1476
The ELAV RNA-stability factor ...... and IRES-mediated translation
@en
P2093
Ching-Yi Chen
Nateka L Jackson
Peter H King
Scott W Blume
Zheng Meng
P2860
P304
P3181
P356
10.1093/NAR/GKI603
P407
P577
2005-05-24T00:00:00Z