A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas - Test2 - elhamkhani - TriplyDB

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

http://www.wikidata.org/entity/Q24811594

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A recurrent stop-codon mutation in succinate dehydrogenase subunit B gene in normal peripheral blood and childhood T-cell acute leukemia Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA Germline mutations in TMEM127 confer susceptibility to pheochromocytoma miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity Coordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphoma Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells Pheochromocytomas and Paragangliomas: Clinical and Genetic Approaches Succinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5 Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?An update on the genetics of pheochromocytoma Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Target therapy in metastatic pheochromocytoma: current perspectives and controversies Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma Mitochondrial tumour suppressors: a genetic and biochemical update Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis.The Warburg effect is genetically determined in inherited pheochromocytomas Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma.Bone metastases and skeletal-related events in patients with malignant pheochromocytoma and sympathetic paraganglioma Succinate-to-fumarate ratio as a new metabolic marker to detect the presence of SDHB/D-related paraganglioma: initial experimental and ex vivo findings.Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway.Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas Molecular markers of paragangliomas/pheochromocytomas Succinate is an inflammatory signal that induces IL-1β through HIF-1α.Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis.Mitochondrial Deficiencies in the Predisposition to Paraganglioma SDHA is a tumor suppressor gene causing paraganglioma.Integrative epigenomic and genomic analysis of malignant pheochromocytoma.MicroRNA expression profiling in benign (sporadic and hereditary) and recurring adrenal pheochromocytomas.Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma.Comparative evaluation of set-level techniques in predictive classification of gene expression samples.Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatment Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations.Metastatic paraganglioma.Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.Succinate dehydrogenase-deficient gastrointestinal stromal tumors.Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.

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P2860

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

http://www.wikidata.org/entity/Q24811594

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

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A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

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A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@nl

type

label

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@ast

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@en

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@nl

prefLabel

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@ast

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@en

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

@nl

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JOURNAL.PGEN.0010008

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A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

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Andrew L Kung

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Arthur S Tischler

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Ashley Grossman

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Bruce G Robinson

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Charles D Stiles

http://www.w3.org/2001/XMLSchema#string

Cheng Li

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César Y Hayashida

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Deborah J Marsh

http://www.w3.org/2001/XMLSchema#string

Diana E Benn

http://www.w3.org/2001/XMLSchema#string

Francis Moore

http://www.w3.org/2001/XMLSchema#string

P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

Cluster analysis and display of genome-wide expression patterns

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

Architecture of succinate dehydrogenase and reactive oxygen species generation

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

Molecular basis of the VHL hereditary cancer syndrome

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72-80

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3737316

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10.1371/JOURNAL.PGEN.0010008

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P433

1

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1

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Márta Korbonits

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2005-07-01T00:00:00Z

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7656579

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16103922

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phaeochromocytoma

P932

1183527

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