Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. - Test2 - elhamkhani - TriplyDB

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.

http://www.wikidata.org/entity/Q33277841

about

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia siRNA Versus miRNA as Therapeutics for Gene Silencing Functional genomic and high-content screening for target discovery and deconvolution The Prp19 complex directly functions in mitotic spindle assembly Novel siRNA delivery system to target podocytes in vivo Abasic pivot substitution harnesses target specificity of RNA interference A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 Target mRNA abundance dilutes microRNA and siRNA activity Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.In silico target-specific siRNA design based on domain transfer in heterogeneous data.Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data.Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.MISSION esiRNA for RNAi screening in mammalian cells Synthetic lethality: emerging targets and opportunities in melanoma.The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells Using functional genetics to understand breast cancer biology The role of melanin concentrating hormone (MCH) in the central chemoreflex: a knockdown study by siRNA in the lateral hypothalamus in rats.Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection The mammalian INO80 chromatin remodeling complex is required for replication stress recovery.SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents.Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development.Simultaneous analysis of large-scale RNAi screens for pathogen entry.Functional analysis of the microtubule-interacting transcriptome.Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation.Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer.siRNAs with decreased off-target effect facilitate the identification of essential genes in cancer cells.Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene.Quantitative genetic-interaction mapping in mammalian cells.SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents Design of siRNA Therapeutics from the Molecular Scale The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

P2860

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P2860

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.

http://www.wikidata.org/entity/Q33277841

description

2007 nî lūn-bûn

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2007 թուականի Մարտին հրատարակուած գիտական յօդուած

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2007 թվականի մարտին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Genome-wide resources of endor ...... ific loss-of-function studies.

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Genome-wide resources of endor ...... ific loss-of-function studies.

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type

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Genome-wide resources of endor ...... ific loss-of-function studies.

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Genome-wide resources of endor ...... ific loss-of-function studies.

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Genome-wide resources of endor ...... ific loss-of-function studies.

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Genome-wide resources of endor ...... ific loss-of-function studies.

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Genome-wide resources of endor ...... ific loss-of-function studies.

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Anne-Kristin Heninger

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Antonio Caldarelli

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Bernd Korn

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Birte Sönnichsen

http://www.w3.org/2001/XMLSchema#string

Christoph Sachse

http://www.w3.org/2001/XMLSchema#string

Corina Frenzel

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Effi Rees

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Gabriele Putz

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Hannes Grabner

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Jan Wagner

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P2860

Gene ontology: tool for the unification of biology

DEQOR: a web-based tool for the design and quality control of siRNAs

siRNA target site secondary structure predictions using local stable substructures

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

A system for stable expression of short interfering RNAs in mammalian cells

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Second-generation shRNA libraries covering the mouse and human genomes

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

Rational siRNA design for RNA interference

P2888

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337-344

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scholarly article

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10.1038/NMETH1025

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4

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4

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Bianca Habermann

Aimee L. Jackson

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2007-03-11T00:00:00Z

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1026991209

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