Preferential binding of a G-quadruplex ligand to human chromosome ends. - Test2 - elhamkhani - TriplyDB

Preferential binding of a G-quadruplex ligand to human chromosome ends.

Preferential binding of a G-quadruplex ligand to human chromosome ends.

http://www.wikidata.org/entity/Q24815673

about

5'-UTR RNA G-quadruplexes: translation regulation and targeting G-quadruplexes and their regulatory roles in biology Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines Targeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.ATR contributes to telomere maintenance in human cells Structural insights into G-quadruplexes: towards new anticancer drugs.Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.How long is too long? Effects of loop size on G-quadruplex stability.Novel G-quadruplex stabilizing agents: in-silico approach and dynamics.Impact of G-quadruplex structures and intronic polymorphisms rs17878362 and rs1642785 on basal and ionizing radiation-induced expression of alternative p53 transcripts A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).Excited state proton transfer of natural flavonoids and their chromophores in duplex and tetraplex DNAs Advancing small-molecule-based chemical biology with next-generation sequencing technologies.Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage.Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex [d(TGGGGT)]4 and cyanine dye 2,2'-diethyl-9-methyl-selenacarbocyanine bromide G-quadruplex structures and G-quadruplex-interactive compounds.Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells A hitchhiker's guide to G-quadruplex ligands.Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.Folding and unfolding pathways of the human telomeric G-quadruplex.Structural identity of telomeric complexes.Telomeres as targets for anticancer therapies.Targeting non-B-form DNA in living cells.G-quadruplex interacting small molecules and drugs: from bench toward bedside.Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death.Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif.Structure and stability of higher-order human telomeric quadruplexes.G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy.Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex.G-quadruplex structures are stable and detectable in human genomic DNA.Role of ATM in the telomere response to the G-quadruplex ligand 360A.Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.An integrated molecular dynamics (MD) and experimental study of higher order human telomeric quadruplexes.

P2860

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P2860

Preferential binding of a G-quadruplex ligand to human chromosome ends.

http://www.wikidata.org/entity/Q24815673

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Preferential binding of a G-quadruplex ligand to human chromosome ends

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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type

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Preferential binding of a G-quadruplex ligand to human chromosome ends

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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Preferential binding of a G-quadruplex ligand to human chromosome ends

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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Preferential binding of a G-quadruplex ligand to human chromosome ends.

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Nucleic Acids Research

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Preferential binding of a G-quadruplex ligand to human chromosome ends

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Bernard Dutrillaux

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Dennis Gomez

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Eliane Mandine

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Françoise Hoffschir

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Jean-François Riou

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Lydia Riou

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Patrick Mailliet

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P2860

Initial sequencing and analysis of the human genome

Crystal structure of parallel quadruplexes from human telomeric DNA

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

A survey of telomerase activity in human cancer

Interactions of cryptolepine and neocryptolepine with unusual DNA structures.

Natural and pharmacological regulation of telomerase

Targeting human telomerase for cancer therapeutics.

Energetics of strand-displacement reactions in triple helices: a spectroscopic study.

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4182-4190

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scholarly article

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10.1093/NAR/GKI722

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13

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33

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Jean-Louis Mergny

Laurent R Gauthier

Christine Granotier-Beckers

Francois Boussin

Gaelle Pennarun

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2005-07-28T00:00:00Z

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7693831

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16052031

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1181860

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