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Prevalence of quadruplexes in the human genome.Telomeres, telomerase, and tumorigenesis--a review5'-UTR RNA G-quadruplexes: translation regulation and targetingIn vivo veritas: using yeast to probe the biological functions of G-quadruplexesThe unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolusOverexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescenceThe effect of osmolytes and small molecule on Quadruplex-WC duplex equilibrium: a fluorescence resonance energy transfer study.Preferential binding of a G-quadruplex ligand to human chromosome ends.The solution structure of an essential stem-loop of human telomerase RNAStructure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solutionHuman Ku70/80 associates physically with telomerase through interaction with hTERTTopoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres.Multivariate curve resolution: a powerful tool for the analysis of conformational transitions in nucleic acids.Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effectA sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes.Targeting human telomerase for cancer therapeutics.Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.Combined analysis of cell growth and apoptosis-regulating proteins in HPVs associated anogenital tumors.Novel isolation and biochemical characterization of immortalized fibroblasts for tissue engineering vocal fold lamina propria.Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Viral control of vTR expression is critical for efficient formation and dissemination of lymphoma induced by Marek's disease virus (MDV).Identification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening.Single molecule force spectroscopy on G-quadruplex DNA"One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Telomeric repeat-containing RNA structure in living cells.Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.Interactions of actinomycin D with human telomeric G-quadruplex DNA.Telomeres and aging.A Discovery Funnel for Nucleic Acid Binding Drug CandidatesDifferent loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution.Highly fluorescent guanosine mimics for folding and energy transfer studiesMMP-9 silencing regulates hTERT expression via β1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells.Downregulation of telomerase maintenance-related ACD expression in patients undergoing immunosuppresive therapy following kidney transplantation3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffoldTreatment of viral and neoplastic diseases with double-stranded RNA derivatives and other new agents.Stability and kinetics of G-quadruplex structuresFour-stranded DNA: cancer, gene regulation and drug development.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Natural and pharmacological regulation of telomerase
@ast
Natural and pharmacological regulation of telomerase
@en
type
label
Natural and pharmacological regulation of telomerase
@ast
Natural and pharmacological regulation of telomerase
@en
prefLabel
Natural and pharmacological regulation of telomerase
@ast
Natural and pharmacological regulation of telomerase
@en
P2093
P2860
P356
P1476
Natural and pharmacological regulation of telomerase
@en
P2093
Eric Gilson
Jean-François Riou
Patrick Mailliet
P2860
P304
P356
10.1093/NAR/30.4.839
P407
P577
2002-02-01T00:00:00Z