Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity.
about
The coding/non-coding overlapping architecture of the gene encoding the Drosophila pseudouridine synthaseSHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPsDynamic association and localization of human H/ACA RNP proteinsGenetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10Pseudouridines in spliceosomal snRNAsH/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modificationStructure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNAStructural and functional evidence of high specificity of Cbf5 for ACA trinucleotideReconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthaseDifferent mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs.Structure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation.The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification.Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity.Formation of the conserved pseudouridine at position 55 in archaeal tRNAThe structure and function of small nucleolar ribonucleoproteins.Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities.RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation.How a single protein complex accommodates many different H/ACA RNAs.Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAsRNA pseudouridylation: new insights into an old modificationNoncoding RNAs of the H/ACA family.Unveiling substrate RNA binding to H/ACA RNPs: one side fits all.The PUA domain - a structural and functional overview.Insight into the Protein Components of the Box H/ACA RNPStructures of ribonucleoprotein particle modification enzymes.Ribonucleoproteins in archaeal pre-rRNA processing and modification.Analysis of the binding of the N-terminal conserved domain of yeast Cbf5p to a box H/ACA snoRNA.Assembly and trafficking of box C/D and H/ACA snoRNPsProgress in Human and Tetrahymena Telomerase Structure Determination.Human intron-encoded AluACA RNAs and telomerase RNA share a common element promoting RNA accumulation.Revisiting the structure/function relationships of H/ACA(-like) RNAs: a unified model for Euryarchaea and Crenarchaea.Long-distance placement of substrate RNA by H/ACA proteins.Posttranscriptional RNA Pseudouridylation.The Role of Noncoding RNA Pseudouridylation in Nuclear Gene Expression Events.Crystal structure of an H/ACA box ribonucleoprotein particle.Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein
P2860
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P2860
Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity.
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2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Crystal structure determinatio ...... roteins in H/ACA sRNP activity
@nl
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@ast
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@en
type
label
Crystal structure determinatio ...... roteins in H/ACA sRNP activity
@nl
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@ast
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@en
prefLabel
Crystal structure determinatio ...... roteins in H/ACA sRNP activity
@nl
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@ast
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@en
P2093
P2860
P356
P1476
Crystal structure determinatio ...... oteins in H/ACA sRNP activity.
@en
P2093
Bruno Charpentier
Christiane Branlant
Christophe Charron
François Godard
Jean-Baptiste Fourmann
Xavier Manival
P2860
P304
P356
10.1093/NAR/GKJ482
P407
P577
2006-02-02T00:00:00Z