Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins
about
Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins.HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmenthNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomeraseAn enhanced H/ACA RNP assembly mechanism for human telomerase RNASHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPsStepwise RNP assembly at the site of H/ACA RNA transcription in human cellsDynamic association and localization of human H/ACA RNP proteinsA computational screen for mammalian pseudouridylation guide H/ACA RNAsGenetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNPMutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenitaReconstitution of archaeal H/ACA small ribonucleoprotein complexes active in pseudouridylationCrystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity.Telomeres, NAFLD and Chronic Liver DiseaseH/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modificationStructure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNAStructure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junctionStructure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding InterfaceReconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthaseCharacterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assemblyPseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism.The cotranscriptional assembly of snoRNPs controls the biosynthesis of H/ACA snoRNAs in Saccharomyces cerevisiae.Telomerase Regulation from Beginning to the EndTelomere maintenance and the etiology of adult gliomaStructure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation.Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants.Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functionsRNA-guided RNA modification: functional organization of the archaeal H/ACA RNPTelomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome.A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivoA proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.Spliceosomal snRNA modifications and their function.Post-transcriptional modification of RNAs by artificial Box H/ACA and Box C/D RNPs.Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity.The many facets of H/ACA ribonucleoproteinsCmRBP50 protein phosphorylation is essential for assembly of a stable phloem-mobile high-affinity ribonucleoprotein complex.
P2860
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P2860
Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Architecture and assembly of m ...... telomerase ribonucleoproteins
@ast
Architecture and assembly of m ...... telomerase ribonucleoproteins
@en
Architecture and assembly of m ...... telomerase ribonucleoproteins
@nl
type
label
Architecture and assembly of m ...... telomerase ribonucleoproteins
@ast
Architecture and assembly of m ...... telomerase ribonucleoproteins
@en
Architecture and assembly of m ...... telomerase ribonucleoproteins
@nl
prefLabel
Architecture and assembly of m ...... telomerase ribonucleoproteins
@ast
Architecture and assembly of m ...... telomerase ribonucleoproteins
@en
Architecture and assembly of m ...... telomerase ribonucleoproteins
@nl
P2860
P3181
P356
P1433
P1476
Architecture and assembly of m ...... telomerase ribonucleoproteins
@en
P2093
U Thomas Meier
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600181
P407
P577
2004-04-21T00:00:00Z