Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1
about
Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosisNeurotransmitter release: the last millisecond in the life of a synaptic vesicleStructural and mutational analysis of functional differentiation between synaptotagmins-1 and -7Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosisDifferential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter releaseActivity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10Crystal structure of the RIM1alpha C2B domain at 1.7 A resolutionSomatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channelsThe importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensorCis- and trans-membrane interactions of synaptotagmin-1Ring-like oligomers of Synaptotagmins and related C2 domain proteinsPtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium.Reconstituting SNARE-mediated membrane fusion at the single liposome level.Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorderCross-linking of phospholipid membranes is a conserved property of calcium-sensitive synaptotagminsInteraction of synaptotagmin with lipid bilayers, analyzed by single-molecule force spectroscopy.A role of complexin-lipid interactions in membrane fusion.Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions.Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivoCalcium sensitive ring-like oligomers formed by synaptotagminLong-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles.Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo.Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin ISynaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.Inside insight to membrane fusionC2B polylysine motif of synaptotagmin facilitates a Ca2+-independent stage of synaptic vesicle priming in vivo.Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening.Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger.Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling.An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.Synaptotagmin C2A loop 2 mediates Ca2+-dependent SNARE interactions essential for Ca2+-triggered vesicle exocytosisAnnexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC.Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles.Enlightening molecular mechanisms through study of protein interactionsInsulin vesicle release: walk, kiss, pause ... then run.Complexin and Ca2+ stimulate SNARE-mediated membrane fusionSynaptic vesicle fusion.The SNAP-25 linker as an adaptation toward fast exocytosis.
P2860
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P2860
Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@ast
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@en
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@nl
type
label
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@ast
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@en
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@nl
prefLabel
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@ast
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@en
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@nl
P2093
P2860
P3181
P356
P1476
Augmenting neurotransmitter re ...... 2+ affinity of synaptotagmin 1
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.0509153102
P407
P577
2005-12-20T00:00:00Z