Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
about
Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosisDynamic binding mode of a Synaptotagmin-1-SNARE complex in solutionStructural and mutational analysis of functional differentiation between synaptotagmins-1 and -7Complexins: small but capablePhotophysics of fluorescent probes for single-molecule biophysics and super-resolution imagingDistinct initial SNARE configurations underlying the diversity of exocytosisSingle-molecule FRET study of SNARE-mediated membrane fusionmiR-153 regulates SNAP-25, synaptic transmission, and neuronal developmentLateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusionComplexin cross-links prefusion SNAREs into a zigzag arrayPhosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitmentLarge conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activityThe importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensorCis- and trans-membrane interactions of synaptotagmin-1Supertertiary structure of the synaptic MAGuK scaffold proteins is conservedSynaptotagmin-1 binds to PIP(2)-containing membrane but not to SNAREs at physiological ionic strengthReconstituting SNARE-mediated membrane fusion at the single liposome level.Mapping membrane protein structure with fluorescence.Phosphatidylinositol 4,5-bisphosphate alters synaptotagmin 1 membrane docking and drives opposing bilayers closer together.Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous.In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter releaseProbabilistic determination of probe locations from distance data.The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation.Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission.Nucleoprotein architectures regulating the directionality of viral integration and excision.Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.Calcium sensitive ring-like oligomers formed by synaptotagminFour-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes.Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I.FRET-based trilateration of probes bound within functional ryanodine receptors.Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23Three-dimensional molecular modeling with single molecule FRET.Small-molecule photostabilizing agents are modifiers of lipid bilayer properties.Beyond the random coil: stochastic conformational switching in intrinsically disordered proteins.Domain orientation in the N-Terminal PDZ tandem from PSD-95 is maintained in the full-length proteinSynaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.
P2860
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P2860
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@ast
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@en
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@nl
type
label
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@ast
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@en
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@nl
prefLabel
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@ast
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@en
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@nl
P2093
P2860
P356
P1476
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.
@en
P2093
Keith R Weninger
Marija Vrljic
Pavel Strop
Steven Chu
Ucheor B Choi
P2860
P2888
P304
P356
10.1038/NSMB.1763
P577
2010-02-21T00:00:00Z