Parkin Regulation and Neurodegenerative Disorders - Test2 - elhamkhani - TriplyDB

Parkin Regulation and Neurodegenerative Disorders

Parkin Regulation and Neurodegenerative Disorders

http://www.wikidata.org/entity/Q26770443

about

Mitochondrial dysfunction in Parkinson's disease Parkinson's Disease: From Pathogenesis to Pharmacogenomics Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes.AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease.Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain.Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-Like Cardiomyocytes.Design Principles of Peptide Based Self-Assembled Nanomaterials.Genetic and epigenetic alterations affecting PARK-2 expression in cervical neoplasm among North Indian patients.Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights.A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders.Alzheimer's disease master regulators analysis: search for potential molecular targets and drug repositioning candidates.Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons The Sources of Reactive Oxygen Species and Its Possible Role in the Pathogenesis of Parkinson's Disease

P2860

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P2860

Parkin Regulation and Neurodegenerative Disorders

http://www.wikidata.org/entity/Q26770443

description

2015 nî lūn-bûn

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2015 թուականին հրատարակուած գիտական յօդուած

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2015 թվականին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Parkin Regulation and Neurodegenerative Disorders

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Parkin Regulation and Neurodegenerative Disorders

@en

Parkin Regulation and Neurodegenerative Disorders

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type

label

Parkin Regulation and Neurodegenerative Disorders

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Parkin Regulation and Neurodegenerative Disorders

@en

Parkin Regulation and Neurodegenerative Disorders

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prefLabel

Parkin Regulation and Neurodegenerative Disorders

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Parkin Regulation and Neurodegenerative Disorders

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Parkin Regulation and Neurodegenerative Disorders

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FNAGI.2015.00248

P1433

Frontiers in Aging Neuroscience

P1476

Parkin Regulation and Neurodegenerative Disorders

@en

P2093

Cheng-Wu Zhang

http://www.w3.org/2001/XMLSchema#string

Kah-Leong Lim

http://www.w3.org/2001/XMLSchema#string

Liting Hang

http://www.w3.org/2001/XMLSchema#string

Tso-Pang Yao

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

Ubiquitin is phosphorylated by PINK1 to activate parkin

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

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248

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scholarly article

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5505

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10.3389/FNAGI.2015.00248

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neurodegeneration

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4709595

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