6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling
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MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancersPubChem BioAssay: 2017 updatePhyscion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinomaTargeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung CancerOncogene-directed alterations in cancer cell metabolism.Deciphering the Effect of Metformin on Prostate Cancer Risk by Ethnicity.Upregulating miR-146a by physcion reverses multidrug resistance in human chronic myelogenous leukemia K562/ADM cells.Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress.Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions.What has passed is prolog: new cellular and physiological roles of G6PD.New Challenges to Study Heterogeneity in Cancer Redox Metabolism.Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370.Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis.The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy.Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress.Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation.The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.Inhibition of Glucose-6-Phosphate Dehydrogenase Reverses Cisplatin Resistance in Lung Cancer Cells via the Redox System.A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.PubChem BioAssay: A Decade's Development toward Open High-Throughput Screening Data SharingMetabolite sensing and signaling in cell metabolismSteroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer CellsPotential involvement of Drosophila flightless-1 in carbohydrate metabolism
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6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling
description
2015 nî lūn-bûn
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2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@ast
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@en
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@nl
type
label
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@ast
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@en
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@nl
prefLabel
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@ast
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@en
6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@nl
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P2860
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P921
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6-Phosphogluconate dehydrogena ...... nhibiting LKB1-AMPK signalling
@en
P2093
Benjamin H Lee
Daniel J Brat
Dongsheng Wang
Fadlo R Khuri
Georgia Zhuo Chen
Hanna J Khoury
Hee-Bum Kang
Jae Ho Seo
P2860
P2888
P304
P3181
P356
10.1038/NCB3255
P407
P577
2015-10-19T00:00:00Z
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P6179
1004052792