MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
about
Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25STRAD pseudokinases regulate axogenesis and LKB1 stabilityComplexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascadeRap2A links intestinal cell polarity to brush border formationMO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinasesLKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation14-3-3 interacts with LKB1 via recognizing phosphorylated threonine 336 residue and suppresses LKB1 kinase functionSIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activationCharacterization of an alternative splice variant of LKB1Signaling by target of rapamycin proteins in cell growth controlMicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cellsAMP-activated protein kinase, stress responses and cardiovascular diseasesHonokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisFyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulationMolecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signallingCrystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptorATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour SuppressorStructural insights into the activation of MST3 by MO25Structure of zebrafish MO25The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPKDiscovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3)Evaluation of MicroRNAs Regulating Anoikis Pathways and Its Therapeutic PotentialSignalling scaffolds and local organization of cellular behaviourSTE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsLKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domainA role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndromeArsenic inhibits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathwayFeeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in DrosophilaExpression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophyThe WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinasesProtein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neuronsScaffolding by ERK3 regulates MK5 in developmentInvestigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activityLKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testisLKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice.Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.Regulation of LKB1/STRAD localization and function by E-cadherin.
P2860
Q21134128-4A1DEB0F-A65F-4A1C-89C4-82D27FCD56F2Q21203071-FE05F758-B287-4163-8641-84FBA36C838FQ21245891-5DF9790F-CD0C-4C13-BBF7-256A8E901CD8Q24293320-0352DA40-5537-45A3-A859-7C7F01D39F68Q24297671-E8C02F76-5D6D-4F4A-9C6B-110F01B51A57Q24310603-15951A45-1A6C-440A-BF33-77BB7EF4F2A4Q24314737-A6A8BCAA-727E-494A-A8BF-9C5A44D867FBQ24319852-CC1883EE-2D12-4819-BDA7-E28B75B7E62EQ24321658-68FF4AB1-D0F5-428A-9C77-12DF897B3E24Q24322647-A557A572-2B67-4FA4-A5E0-D8BC5D422BEDQ24522447-81133D3A-BBB7-4ADC-B8F9-B946D18F54B8Q24603505-FDA3AE6A-EA14-4494-82ED-E76EAFE2398BQ24610297-2AC4D154-64D9-4B55-BBBF-15EF1A93ADCAQ24614006-68459768-4038-4F0D-8B09-16364AF0DD5BQ24634669-E4817BD2-0D25-4699-A62E-48EFB45FFEA7Q24794909-5BFA068B-120C-4AD8-BCA5-AFDF52A5D93CQ26770788-8747B120-518F-4C7B-87CC-4A508C405023Q26781896-86561A08-6DA7-4C7C-AE23-09BFF7642738Q27642975-E73B0C6E-ADD0-4A06-85B8-A78E6D2E4971Q27655851-C20F11CC-CDCD-49B6-9F2E-AF95F9519224Q27675802-2A665ADE-F6CB-4DE5-B71D-21D44E0A2FADQ27679832-1A34B086-8C55-40AA-A85F-CCF0F46FD929Q27682265-68E1656A-D482-4397-B10F-F6DA9D420EEBQ27704783-35C9C556-4FF7-4F66-B3F3-DDF2D1617942Q28084310-C53DC291-B3CF-41EC-BA13-9B0927AED3A4Q28259061-EEFEC759-2269-4CAB-8218-9BAFDC94E67AQ28264138-7537411D-9E60-4450-8B00-DBB5A2EDC83DQ28280001-44E63F1A-2DE9-47C2-AA26-FC19F6E858F6Q28307804-27F4340B-DCFF-4CDD-8BFB-A4FC6295BDCDQ28395380-AD810F23-B6F4-4E10-BB72-7F972DBEBF12Q28547387-056A0B05-B9D0-4764-A56D-9D44BC087DD4Q28580464-3AD81135-9CEB-4408-A005-8DBF8D3DE3A8Q28583124-B775FF0F-D4BA-4505-877F-953EF356569EQ28587247-7FDF5FC5-D8E1-4CFB-8CC8-717D9EBEF401Q28587317-25BC0E66-0EB4-4484-B03F-6FEF3409D5DCQ28591614-64952106-41B5-4641-B7E4-DD41E312FD04Q28742048-AF1A6B31-3217-4E3B-B944-8EAA0C8D17E4Q30404723-3A626DA8-9C48-4A23-A432-D6E50D96B4B4Q30437206-0AD9B4D2-867F-4893-A39C-084CC27B9880Q30437381-50AA5145-FDA9-4EBE-8FC8-6D1F2E006E63
P2860
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@ast
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en-gb
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@nl
type
label
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@ast
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en-gb
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@nl
prefLabel
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@ast
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en-gb
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
MO25alpha/beta interact with S ...... localize LKB1 in the cytoplasm
@en
P2093
Agnieszka Kieloch
Annette F Baas
Hans C Clevers
Nick A Morrice
P2860
P304
P3181
P356
10.1093/EMBOJ/CDG490
P407
P577
2003-10-01T00:00:00Z