Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism - Test2 - elhamkhani - TriplyDB

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

http://www.wikidata.org/entity/Q26782028

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Propagation of prions causing synucleinopathies in cultured cells Prion diseases: immunotargets and therapy Prions, prion-like prionoids, and neurodegenerative disorders Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma Review: Multiple system atrophy: emerging targets for interventional therapies Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation Insights into Mechanisms of Chronic Neurodegeneration Genetics Underlying Atypical Parkinsonism and Related Neurodegenerative Disorders Human-to-mouse prion-like propagation of mutant huntingtin protein.Regulation of cell-non-autonomous proteostasis in metazoans Animal modeling an oligodendrogliopathy--multiple system atrophy Neuromolecular imaging, a nanobiotechnology for Parkinson's disease: advancing pharmacotherapy for personalized medicine.Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.Types and Strains: Their Essential Role in Understanding Protein Aggregation in Neurodegenerative Diseases.Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications Genomic Characteristics of Genetic Creutzfeldt-Jakob Disease Patients with V180I Mutation and Associations with Other Neurodegenerative Disorders.Expanding the prion disease repertoire.Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid.Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells.A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.Parkinson disease and progressive supranuclear palsy: protein expression in skin.Review: Novel treatment strategies targeting alpha-synuclein in multiple system atrophy as a model of synucleinopathy Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders.Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson's disease alpha-synuclein transgenic mice.Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease.Diffusion tensor imaging in the characterization of multiple system atrophy.Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation Phosphorylation induces distinct alpha-synuclein strain formation.Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy.Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.Propagation of pathological α-synuclein in marmoset brain.Natural history of pure autonomic failure: A United States prospective cohort Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases.

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P2860

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

http://www.wikidata.org/entity/Q26782028

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2015 nî lūn-bûn

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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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name

Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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type

label

Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Proceedings of the National Academy of Sciences of the United States of America

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Evidence for α-synuclein prion ...... hy in humans with parkinsonism

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Amanda L Woerman

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David B Berry

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Jennifer K Lowe

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Ryan Rampersaud

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Smita Patel

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P2860

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

Second consensus statement on the diagnosis of multiple system atrophy

Propagation of prions causing synucleinopathies in cultured cells

Neurodegenerative diseases: expanding the prion concept

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Alpha-synuclein in Lewy bodies

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

Novel proteinaceous infectious particles cause scrapie

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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38

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112

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Stanley B. Prusiner

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Parkinson's disease

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