Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
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The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transportersPlasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic BrainGlia as drivers of abnormal neuronal activityDevelopment and regulation of chloride homeostasis in the central nervous systemThe role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disordersCurrent view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2Molecular and evolutionary insights into the structural organization of cation chloride cotransportersA variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formationAge- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transportersModulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives.A novel regulatory locus of phosphorylation in the C terminus of the potassium chloride cotransporter KCC2 that interferes with N-ethylmaleimide or staurosporine-mediated activation.Twenty years of fluorescence imaging of intracellular chlorideA role for intracellular zinc in glioma alteration of neuronal chloride equilibrium.The role of GABA in the regulation of GnRH neuronsDown-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity.Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizuresCation-chloride cotransporters in neuronal development, plasticity and diseaseReactive astrogliosis causes the development of spontaneous seizures.Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic painTherapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic painHomeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone.Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures.Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophreniaPhysiological implications of ocean acidification for marine fish: emerging patterns and new insights.Pilocarpine-induced seizures trigger differential regulation of microRNA-stability related genes in rat hippocampal neuronsKinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminenceK-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function.Regulation of neuronal chloride homeostasis by neuromodulators.Astroglial Scarring and Seizures: A Cell Biological Perspective on Epilepsy.Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.The Timing of the Excitatory-to-Inhibitory GABA Switch Is Regulated by the Oxytocin Receptor via KCC2Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain.Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis.WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter.A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-β2.Early Correlated Network Activity in the Hippocampus: Its Putative Role in Shaping Neuronal Circuits.
P2860
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P2860
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@ast
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@en
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@nl
type
label
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@ast
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@en
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@nl
prefLabel
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@ast
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@en
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@nl
P2093
P2860
P50
P3181
P1476
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2
@en
P2093
Kristopher T Kahle
Liliya Silayeva
Stephen J Moss
Tarek Z Deeb
P2860
P304
P3181
P356
10.1016/J.TINS.2013.08.006
P407
P577
2013-10-15T00:00:00Z