Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 - Test2 - elhamkhani - TriplyDB

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

http://www.wikidata.org/entity/Q26829362

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The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain Glia as drivers of abnormal neuronal activity Development and regulation of chloride homeostasis in the central nervous system The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2 Molecular and evolutionary insights into the structural organization of cation chloride cotransporters A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transporters Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives.A novel regulatory locus of phosphorylation in the C terminus of the potassium chloride cotransporter KCC2 that interferes with N-ethylmaleimide or staurosporine-mediated activation.Twenty years of fluorescence imaging of intracellular chloride A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium.The role of GABA in the regulation of GnRH neurons Down-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity.Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures Cation-chloride cotransporters in neuronal development, plasticity and disease Reactive astrogliosis causes the development of spontaneous seizures.Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone.Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures.Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia Physiological implications of ocean acidification for marine fish: emerging patterns and new insights.Pilocarpine-induced seizures trigger differential regulation of microRNA-stability related genes in rat hippocampal neurons Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence K-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function.Regulation of neuronal chloride homeostasis by neuromodulators.Astroglial Scarring and Seizures: A Cell Biological Perspective on Epilepsy.Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.The Timing of the Excitatory-to-Inhibitory GABA Switch Is Regulated by the Oxytocin Receptor via KCC2 Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain.Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis.WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter.A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2 The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-β2.Early Correlated Network Activity in the Hippocampus: Its Putative Role in Shaping Neuronal Circuits.

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P2860

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

http://www.wikidata.org/entity/Q26829362

description

2013 nî lūn-bûn

@nan

2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@ast

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@en

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@nl

type

label

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@ast

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@en

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@nl

prefLabel

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@ast

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@en

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@nl

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J.TINS.2013.08.006

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Trends in Neurosciences

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Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

@en

P2093

Kristopher T Kahle

http://www.w3.org/2001/XMLSchema#string

Liliya Silayeva

http://www.w3.org/2001/XMLSchema#string

Stephen J Moss

http://www.w3.org/2001/XMLSchema#string

Tarek Z Deeb

http://www.w3.org/2001/XMLSchema#string

P2860

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission

Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters

Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents

Clustering of neuronal K+-Cl- cotransporters in lipid rafts by tyrosine phosphorylation

Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain

Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

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726-737

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4041771

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10.1016/J.TINS.2013.08.006

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12

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36

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Martin Puskarjov

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2013-10-15T00:00:00Z

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258058797

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24139641

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phosphorylation

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4381966

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