Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease - Test2 - elhamkhani - TriplyDB

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

http://www.wikidata.org/entity/Q26853181

about

Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration Approaches of targeting Rho GTPases in cancer drug discovery Function and regulation of the Rho guanine nucleotide exchange factor Trio Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.Yeast translation elongation factor-1A binds vacuole-localized Rho1p to facilitate membrane integrity through F-actin remodeling.Identification of Dck1 and Lmo1 as upstream regulators of the small GTPase Rho5 in Saccharomyces cerevisiae.Rac Attack: Modulation of the Small GTPase Rac in Inflammatory Bowel Disease and Thiopurine Therapy Regulation and function of P-Rex family Rac-GEFs The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer.Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells Overexpression of GEFT, a Rho family guanine nucleotide exchange factor, predicts poor prognosis in patients with rhabdomyosarcoma.DOCK8 regulates signal transduction events to control immunity Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast.Inhibition of Cdc42 and Rac1 activities in pheochromocytoma, the adrenal medulla tumor.Establishment of epithelial polarity--GEF who's minding the GAP?The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia.Using light to shape chemical gradients for parallel and automated analysis of chemotaxis.Fine-Tuning of the Actin Cytoskeleton and Cell Adhesion During Drosophila Development by the Unconventional Guanine Nucleotide Exchange Factors Myoblast City and Sponge.Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization.ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions.ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.Expression of microRNA-10a, microRNA-342-3p and their predicted target gene TIAM1 in extranodal NK/T-cell lymphoma, nasal type.Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice.Cigarette smoke inhibits ROCK2 activation in T cells and modulates IL-22 production Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING The dynamic behavior of Ect2 in response to DNA damage.Deregulation of Rho GTPases in cancer

P2860

Q26739711-D069C37B-CC44-4415-847B-8E9BE6412BE3 Q26751231-61BF4151-EB44-4D0D-935C-CA64F153EE73 Q26782144-8AC4E23A-766E-44CC-A202-7336F33CF5E7 Q26825105-11EF8AC7-2989-4C09-93DD-78D1F67A4760 Q26851300-03A71A34-40E3-4D0F-87C8-A247B9235E54 Q26995528-C7D46429-EF69-4EAA-8B0D-9FEF10012F46 Q27305353-C6878936-4C30-44A3-81EA-850775528865 Q27932582-B04E2778-5C5D-45DB-BDC4-F74CBC87E646 Q27937783-805E7A64-3310-4B10-A2C4-AA5D4EDF75B1 Q28067937-68DC60AF-F59D-492B-932D-98B0C4C43572 Q28087472-0E2AB811-724A-456C-9DFD-AE7389236CA7 Q28115476-CE10F898-BB05-4673-AAE4-D7875A21AEAA Q28304550-FECBC391-25DD-485C-9555-7274E5C0A0E5 Q28541545-31354727-102C-4D7D-9494-2642816E06DF Q28550876-67EF1F0C-0225-460E-9CEF-C5379A16176B Q30361921-52BAFF32-5567-4FB2-B2A9-6B1FB86891FB Q30601549-BFB50384-91F7-44DA-BC07-19664FDAC1FA Q30810814-8DD7C7A7-B673-4DF1-9F05-2D99EB266582 Q33563360-5288AB0F-276F-4AD7-8E90-693135821E43 Q33583005-698B23E6-BFD4-49CC-96D6-0B442E53B237 Q33652131-FDE440F9-64DE-4DD0-AB81-E407FC5BBE0A Q33701440-98C785EC-B9A7-4B7E-A1F6-E56EA1B60ACE Q33777707-EF73D049-7D9B-4886-A243-B133D509C8C5 Q33980507-FCE4436A-D9CD-4350-94C1-F4CA22E4F3A5 Q34478364-85299C32-CE88-4605-A09B-71A73392D032 Q35000289-57D57B4D-EC1D-4D8A-B2A8-19919E255805 Q35238551-98FE1745-8151-4318-BF7A-F85A707712FC Q35577198-4193E8DB-864A-44D1-A476-D6795AC0FB42 Q35821089-0E7B7B3C-9F10-4A13-8150-3A7F1CA51317 Q36014654-3D727A57-2845-466F-B646-D4BF6863903B Q36113595-543BF12D-C6C8-451F-8A96-55EB67B29C0E Q36119815-BC6C1F1D-6B59-4D76-B65F-47FC9AD8BC93 Q36147109-9417F280-2F9D-432F-AD4E-918112A4734C Q36256649-CFD9064D-2472-4C1A-8BB4-7CA1C1767A50 Q36502791-BBD3FC9C-10B9-46DB-8631-48CC8CB4CDC7 Q36675069-A0785EB0-5D0C-46F0-B751-EFA59118125C Q36701228-B2E92A83-CD89-4743-8AB3-21AB645BDD2C Q36744738-2F802C0C-9FAA-43B6-BE0C-C6F524CFBB03 Q36796076-A5695A2A-35DC-4EE8-B889-CDCA193E8194 Q37214445-6F104BA9-C7A3-4D2B-BFA0-57E01EA2891A

P2860

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

http://www.wikidata.org/entity/Q26853181

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Rho guanine nucleotide exchang ...... ity in development and disease

@ast

Rho guanine nucleotide exchang ...... ity in development and disease

@en

Rho guanine nucleotide exchang ...... ity in development and disease

@nl

type

label

Rho guanine nucleotide exchang ...... ity in development and disease

@ast

Rho guanine nucleotide exchang ...... ity in development and disease

@en

Rho guanine nucleotide exchang ...... ity in development and disease

@nl

prefLabel

Rho guanine nucleotide exchang ...... ity in development and disease

@ast

Rho guanine nucleotide exchang ...... ity in development and disease

@en

Rho guanine nucleotide exchang ...... ity in development and disease

@nl

P1433

Q26853181-D83C6113-F695-44F8-B2B0-32B7AAC5DA2D

P1476

Q26853181-57FDC849-1253-4CC7-9D79-4D4518D77EF5

P2093

Q26853181-0C0E7F7C-7FB5-4B10-8480-06A9E1E6DB0C

Q26853181-3BAEB75A-BAD8-4E0E-8909-C70378AA7655

Q26853181-89FF7DE4-D9C1-428C-ADB5-534255962054

P2860

Q26853181-0073D384-A3B0-4867-82A0-8E6EEC776DFC

Q26853181-01569E63-539F-4E2C-9EDF-86F5847D809A

Q26853181-02689DB9-D87F-45A3-A242-F78134FFF909

Q26853181-057B76E8-73CE-4A52-B8F2-F1CA5B2F8EF3

Q26853181-06D54CA3-673B-4C27-BF01-B35FE95081A1

Q26853181-073CDC77-4B18-4157-BAD9-809D7920161C

Q26853181-089ABC16-575D-4A1F-BD7A-6EF4124DA0E5

Q26853181-08F60F39-2E3E-44E9-80BB-051EFBD81B96

Q26853181-0B57795A-75ED-4E77-A4E0-23B4E7C3975A

Q26853181-0D2454A2-CF59-4B0A-A2A0-3B1E7F79C3A1

P2888

Q26853181-E23E3C75-4084-47EE-BABF-08035A672776

P304

Q26853181-0F801ABB-0757-4AF2-BC34-1E72EACA11A7

P31

Q26853181-0C880BDE-48A0-4870-8B83-6A5CFFAE52B8

P3181

Q26853181-20074FEB-CDE3-4E8D-8BE3-973E2FA1A6CB

P356

Q26853181-8DB0695E-CC53-44D0-A2E0-81D70957B94E

P407

Q26853181-4ED49640-6284-411A-99C2-7AE8A3DA8B4E

P433

Q26853181-44A51E62-FBF5-4422-B55D-02B6A3C800CD

P478

Q26853181-D6DC04B5-45F6-4CFE-B5ED-5DFAA2686962

P577

Q26853181-E00655FB-86B9-4673-A7EB-FB1114FE4192

P5875

Q26853181-51E15F33-0B29-4497-A903-FBBD8B8329D1

P6179

Q26853181-32FC3737-1E0C-43E2-B802-92E9010C9CCA

P698

Q26853181-78962019-C399-4FEE-BB4C-CE5A44D8237F

P932

Q26853181-57DF5EEB-92A1-4112-A961-739A3865A5C4

P3181

P356

P1433

P1476

Rho guanine nucleotide exchang ...... ity in development and disease

@en

P2093

C J Der

http://www.w3.org/2001/XMLSchema#string

D R Cook

http://www.w3.org/2001/XMLSchema#string

K L Rossman

http://www.w3.org/2001/XMLSchema#string

P2860

Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation

Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering

Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.

P2888

P304

4021-35

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2077465

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/ONC.2013.362

http://www.w3.org/2001/XMLSchema#string

P407

P433

31

http://www.w3.org/2001/XMLSchema#string

P478

33

http://www.w3.org/2001/XMLSchema#string

P577

2014-07-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

256612043

http://www.w3.org/2001/XMLSchema#string

P6179

1017498052

http://www.w3.org/2001/XMLSchema#string

P698

24037532

http://www.w3.org/2001/XMLSchema#string

P932

4875565

http://www.w3.org/2001/XMLSchema#string