mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions - Test2 - elhamkhani - TriplyDB

mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

http://www.wikidata.org/entity/Q27007511

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ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer.Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1.Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells.Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma.Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism.Hydrogen sulphide exacerbates acute pancreatitis by over-activating autophagy via AMPK/mTOR pathway.Autophagy Induced by Areca Nut Extract Contributes to Decreasing Cisplatin Toxicity in Oral Squamous Cell Carcinoma Cells: Roles of Reactive Oxygen Species/AMPK Signaling Dual abrogation of MNK and mTOR: a novel therapeutic approach for the treatment of aggressive cancers.mTOR inhibitors in urinary bladder cancer.Inhibition of mTOR's Catalytic Site by PKI-587 Is a Promising Therapeutic Option for Gastroenteropancreatic Neuroendocrine Tumor Disease.Molecular signaling cascades involved in nonmelanoma skin carcinogenesis.Eukaryotic translation initiation factors and cancer.Long non-coding RNA-CRNDE: a novel regulator of tumor growth and angiogenesis in hepatoblastoma PERK Signal-Modulated Protein Translation Promotes the Survivability of Dengue 2 Virus-Infected Mosquito Cells and Extends Viral Replication.Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish.Ferulic Acid Promotes Hypertrophic Growth of Fast Skeletal Muscle in Zebrafish Model.Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum.C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation.Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.Concise Review: Advanced Cell Culture Models for Diamond Blackfan Anemia and Other Erythroid Disorders.Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature.Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation.Alzheimer's Disease and Type 2 Diabetes: A Critical Assessment of the Shared Pathological Traits.Translation acrobatics: how cancer cells exploit alternate modes of translational initiation

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mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

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2014 nî lūn-bûn

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2014 թուականին հրատարակուած գիտական յօդուած

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2014年の論文

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2014年论文

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mTOR Signaling in Protein Tran ...... and Therapeutic Interventions

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Molecular Biology International

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mTOR Signaling in Protein Tran ...... and Therapeutic Interventions

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Mehvish Showkat

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Mushtaq A Beigh

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American society of clinical oncology meeting

Overexpression of s6 kinase 1 in brain tumours is associated with induction of hypoxia-responsive genes and predicts patients' survival

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells

Identification of Protor as a novel Rictor-binding component of mTOR complex-2

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

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686984

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scholarly article

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142610

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10.1155/2014/686984

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2014

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Khurshid I. Andrabi

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2014-11-20T00:00:00Z

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269715674

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25505994

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4258317

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