Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?
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Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseNeuronal Mitophagy in Neurodegenerative DiseasesImmunization Against Specific Fragments of Neurotrophin p75 Receptor Protects Forebrain Cholinergic Neurons in the Olfactory Bulbectomized MiceNeuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function.miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease.Iron and Neurodegeneration: Is Ferritinophagy the Link?Brain Under Stress and Alzheimer's Disease.Study of Exosomes Shed New Light on Physiology of Amyloidogenesis.Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.Autophagy and Alzheimer's Disease.Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Critical importance of RAB proteins for synaptic function.Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases.Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease.GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.Disruption of amyloid precursor protein ubiquitination selectively increases amyloid β (Aβ) 40 levels via presenilin 2-mediated cleavage.Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures.Organellar Omics-A Reviving Strategy to Untangle the Biomolecular Complexity of the Cell.Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions.Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.Bin1 and CD2AP polarize Aβ generation in neurons.Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice.Regulated intramembrane proteolysis: emergent role in cell signalling pathways.Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells.Rab GTPases and Membrane Trafficking in Neurodegeneration.Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease.Modulation of Mitochondrial Dynamics in Neurodegenerative Diseases: An Insight Into Prion Diseases
P2860
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P2860
Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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name
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@ast
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@en
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@nl
type
label
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@ast
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@en
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@nl
prefLabel
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@ast
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@en
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@nl
P2860
P921
P3181
P1476
Early etiology of Alzheimer's ...... hagy or endosomal dysfunction?
@en
P2093
Aleksandar Peric
Wim Annaert
P2860
P2888
P304
P3181
P356
10.1007/S00401-014-1379-7
P407
P577
2015-03-01T00:00:00Z
P5875
P6179
1020162742