Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy
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Tamoxifen Resistance: Emerging Molecular TargetsTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsAberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceHedgehog Signaling in Malignant Pleural MesotheliomaAutophagy and regulation of cilia function and assemblyEpidermal growth factor signaling in transformed cellsGata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb DevelopmentDYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistanceThymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.Hedgehog signaling pathway in colorectal cancer: function, mechanism, and therapy.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.A role for smoothened during murine lens and cornea development.Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened.Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cellsUnderstanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid2.Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signalingAberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.Non-melanoma skin cancer: new and future synthetic drug treatments.Hedgehog Gli signalling in kidney fibrosis.Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.Targeting the hedgehog signaling pathway for cardiac repair and regeneration.The Hedgehog Signaling Networks in Lung Cancer: The Mechanisms and Roles in Tumor Progression and Implications for Cancer Therapy.From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases.Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility.Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus.Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradationThe ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI.An old friend with new skills: Imiquimod as novel inhibitor of Hedgehog signaling in basal cell carcinoma.Opposing Shh and Fgf signals initiate nasotemporal patterning of the zebrafish retina.
P2860
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P2860
Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Context-dependent signal integ ...... mplications for cancer therapy
@ast
Context-dependent signal integ ...... mplications for cancer therapy
@en
Context-dependent signal integ ...... mplications for cancer therapy
@nl
type
label
Context-dependent signal integ ...... mplications for cancer therapy
@ast
Context-dependent signal integ ...... mplications for cancer therapy
@en
Context-dependent signal integ ...... mplications for cancer therapy
@nl
prefLabel
Context-dependent signal integ ...... mplications for cancer therapy
@ast
Context-dependent signal integ ...... mplications for cancer therapy
@en
Context-dependent signal integ ...... mplications for cancer therapy
@nl
P2860
P921
P3181
P1476
Context-dependent signal integ ...... mplications for cancer therapy
@en
P2093
Ariel Ruiz I Altaba
P2860
P304
P3181
P356
10.1016/J.SEMCDB.2014.05.003
P407
P5008
P577
2014-05-19T00:00:00Z