Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 - Test2 - elhamkhani - TriplyDB

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

http://www.wikidata.org/entity/Q27308072

about

Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.Thwarting endogenous stress: BRCA protects against aldehyde toxicity.BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability.Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer.RPA and RAD51: fork reversal, fork protection, and genome stability

P2860

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P2860

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

http://www.wikidata.org/entity/Q27308072

description

2016 nî lūn-bûn

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2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@ast

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@en

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@nl

type

label

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@ast

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@en

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@nl

prefLabel

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@ast

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@en

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@nl

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JOURNAL.PGEN.1006236

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P1476

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

@en

P2093

Betty Martin

http://www.w3.org/2001/XMLSchema#string

Diana C Haines

http://www.w3.org/2001/XMLSchema#string

Eileen Southon

http://www.w3.org/2001/XMLSchema#string

Lino Tessarollo

http://www.w3.org/2001/XMLSchema#string

Rajanikant Chittela

http://www.w3.org/2001/XMLSchema#string

Sandra Burkett

http://www.w3.org/2001/XMLSchema#string

Shyam K Sharan

http://www.w3.org/2001/XMLSchema#string

Xia Ding

http://www.w3.org/2001/XMLSchema#string

P2860

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats

Structural basis for recruitment of BRCA2 by PALB2

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

Simple and highly efficient BAC recombineering using galK selection

Molding BRCA2 function through its interacting partners

Molecular views of recombination proteins and their control

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

P304

e1006236

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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4131212

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10.1371/JOURNAL.PGEN.1006236

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P433

8

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12

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Suzanne A Hartford

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2016-08-04T00:00:00Z

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27490902

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4973925

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