about
Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairStructural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assemblySusceptibility pathways in Fanconi's anemia and breast cancerPancreatic Cancer GeneticsThe expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2Structure and function of WD40 domain proteinsHomologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsMolding BRCA2 function through its interacting partnersPALB2: the hub of a network of tumor suppressors involved in DNA damage responsesMitotic homologous recombination maintains genomic stability and suppresses tumorigenesisCooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombinationNovel peptide-mediated interactions derived from high-resolution 3-dimensional structuresCancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifFunctional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistanceMale fertility defect associated with disrupted BRCA1-PALB2 interaction in micePlasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.PALB2/FANCN: recombining cancer and Fanconi anemia.Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada.Mutations in BRCA2 and PALB2 in male breast cancer cases from the United StatesGrowing recognition of the role for rare missense substitutions in breast cancer susceptibilityInitial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673.PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and functionA Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour DevelopmentHomologous recombination and its regulationFunctional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancerMDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombinationPoly(ADP-Ribose) Mediates the BRCA2-Dependent Early DNA Damage Response.Prevalence of PALB2 mutations in Australasian multiple-case breast cancer familiesPALB2 and breast cancer: ready for clinical translation!BRCA1 and BRCA2: different roles in a common pathway of genome protection.PALB2 mutations in familial breast and pancreatic cancer.Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM.A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.Functional assays for analysis of variants of uncertain significance in BRCA2.Next-generation sequencing for inherited breast cancer risk: counseling through the complexity.Therapeutic opportunities within the DNA damage response.Long-term, large scale cryopreservation of insect cells at -80 °C
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis for recruitment of BRCA2 by PALB2
@ast
Structural basis for recruitment of BRCA2 by PALB2
@en
Structural basis for recruitment of BRCA2 by PALB2
@en-gb
Structural basis for recruitment of BRCA2 by PALB2
@nl
type
label
Structural basis for recruitment of BRCA2 by PALB2
@ast
Structural basis for recruitment of BRCA2 by PALB2
@en
Structural basis for recruitment of BRCA2 by PALB2
@en-gb
Structural basis for recruitment of BRCA2 by PALB2
@nl
prefLabel
Structural basis for recruitment of BRCA2 by PALB2
@ast
Structural basis for recruitment of BRCA2 by PALB2
@en
Structural basis for recruitment of BRCA2 by PALB2
@en-gb
Structural basis for recruitment of BRCA2 by PALB2
@nl
P2860
P50
P3181
P356
P1433
P1476
Structural basis for recruitment of BRCA2 by PALB2
@en
P2093
Sally Swift
P2860
P3181
P356
10.1038/EMBOR.2009.126
P407
P577
2009-09-01T00:00:00Z