The structures of four macrolide antibiotics bound to the large ribosomal subunit
about
The origin of a derived superkingdom: how a gram-positive bacterium crossed the desert to become an archaeonElongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-TuThe methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNAAlterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristinPOPSCOMP: an automated interaction analysis of biomolecular complexes.Prescribing azithromycinAntibiotics that target protein synthesisL11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopyHigh resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelaeThe Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and GirodazoleMolecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine † , ‡DNA mimicry by a high-affinity anti-NF- B RNA aptamerAnalysis of Transient and Catalytic Desosamine-binding Pockets in Cytochrome P-450 PikC from Streptomyces venezuelaeStructural Analysis of QdtB, an Aminotransferase Required for the Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α- d -glucose † ‡U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortuiThe structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibioticsStructural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug actionRevisiting the structures of several antibiotics bound to the bacterial ribosomeMolecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptideFrom Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials.Targeting Antibiotic ResistanceThe bacterial ribosome as a target for antibioticsAccurate structural correlations from maximum likelihood superpositionsMolecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complexImpact of ribosomal modification on the binding of the antibiotic telithromycin using a combined grand canonical monte carlo/molecular dynamics simulation approachCrystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.Ribosomes containing mutants of L4 ribosomal protein from Thermus thermophilus display multiple defects in ribosomal functions and sensitivity against erythromycin.Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets.The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.Kinetics of macrolide action: the josamycin and erythromycin cases.Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis.Comprehensive genetic selection revealed essential bases in the peptidyl-transferase centerRecombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics.Discovery and analysis of 4H-pyridopyrimidines, a class of selective bacterial protein synthesis inhibitors.Molecular mechanisms by which rRNA mutations confer resistance to clindamycinPreparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels-Alder reactionsChalcomycins from Marine-Derived Streptomyces sp. and Their Antimicrobial Activities.Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain.
P2860
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P2860
The structures of four macrolide antibiotics bound to the large ribosomal subunit
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@ast
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@en
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@nl
type
label
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@ast
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@en
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@nl
prefLabel
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@ast
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@en
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@nl
P2093
P3181
P1433
P1476
The structures of four macrolide antibiotics bound to the large ribosomal subunit
@en
P2093
Jeffrey L Hansen
Joseph A Ippolito
Peter B Moore
Thomas A Steitz
P304
P3181
P356
10.1016/S1097-2765(02)00570-1
P577
2002-07-01T00:00:00Z