U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
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Targeting translation initiation in breast cancerStructures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortuiThe structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibioticsStructures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug actionPharmacokinetic study of omacetaxine mepesuccinate administered subcutaneously to patients with advanced solid and hematologic tumorsPhase 2 study of subcutaneous omacetaxine mepesuccinate for chronic-phase chronic myeloid leukemia patients resistant to or intolerant of tyrosine kinase inhibitors.Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemiaHomoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell linesInvestigation into omacetaxine solution stability for in vitro study.Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line.The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide.Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expressionDeubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemiaTrends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.The roles of RNA in the synthesis of protein.Neutrons, magnets, and photons: a career in structural biology.The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocinHomoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells.Emerging therapeutics targeting mRNA translationPateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cellsHigh-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinomaRecent Advances in the Development of Antineoplastic Agents Derived from Natural ProductsTherapeutic interventions to disrupt the protein synthetic machinery in melanomaStructures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.Homoharringtonine binds to and increases myosin-9 in myeloid leukaemiaPharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumorsInhibitory effect of magnetic Fe3O4 nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro.Homoharringtonine and omacetaxine for myeloid hematological malignancies.On the specificity of antibiotics targeting the large ribosomal subunit.Are pleuromutilin antibiotics finally fit for human use?Elements of ribosomal drug resistance and specificity.Omacetaxine mepesuccinate (synribo) - newly launched in chronic myeloid leukemia.Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia.Fungal natural products in research and development.Brusatol overcomes chemoresistance through inhibition of protein translation.A safety evaluation of omacetaxine mepesuccinate for the treatment of chronic myeloid leukemia.Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.Crystal structure of eukaryotic ribosome and its complexes with inhibitors.
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U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@ast
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@en
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@nl
type
label
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@ast
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@en
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@nl
prefLabel
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@ast
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@en
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@nl
P2093
P2860
P3181
P1476
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
@en
P2093
Gregor Blaha
Güliz Gürel
Peter B Moore
Thomas A Steitz
P2860
P304
P3181
P356
10.1016/J.JMB.2009.04.005
P407
P577
2009-05-29T00:00:00Z