Design, activity, and structure of a highly specific artificial endonuclease
about
Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffoldsZinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modificationsStructural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factorEfficient targeting of a SCID gene by an engineered single-chain homing endonucleaseGeneration of DNA cleavage specificities of type II restriction endonucleases by reassortment of target recognition domainsA combinatorial approach to create artificial homing endonucleases cleaving chosen sequencesCatalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificitiesHoming endonuclease I-CreI derivatives with novel DNA target specificitiesI-ApeKI [corrected]: a novel intron-encoded LAGLIDADG homing endonuclease from the archaeon, Aeropyrum pernix K1Genome-editing Technologies for Gene and Cell TherapyHoming endonucleases: DNA scissors on a missionCoevolution of a Homing Endonuclease and Its Host Target SequenceStructure of a designed, right-handed coiled-coil tetramer containing all biological amino acidsDesigned protein-protein associationIntersubunit linker length as a modifier of protein stability: Crystal structures and thermostability of mutant TRAPCrystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineeringGeneration of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteinsMetal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein HomodimerVisualizing phosphodiester-bond hydrolysis by an endonucleaseGenome editing. The new frontier of genome engineering with CRISPR-Cas9Gene targeting using zinc finger nucleasesOctarellin VI: using rosetta to design a putative artificial (β/α)8 proteinAddressing biological uncertainties in engineering gene circuitsRosettaBackrub--a web server for flexible backbone protein structure modeling and designDesign of multi-specificity in protein interfacesHighly Efficient Sex Chromosome Interchanges Produced By I-CreI Expression in DrosophilaGenerating, Maintaining, and Exploiting Diversity in a Memetic Algorithm for Protein Structure Prediction.Practically useful: what the Rosetta protein modeling suite can do for youSpecificity in computational protein designAchievements and Challenges in Computational Protein Design.Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C2H2 zinc fingers.The plant proteome folding project: structure and positive selection in plant protein familiesLAHEDES: the LAGLIDADG homing endonuclease database and engineering serverFlow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleasesComputer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences.Control of catalytic efficiency by a coevolving network of catalytic and noncatalytic residues.Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI.Anchored design of protein-protein interfaces.Mining endonuclease cleavage determinants in genomic sequence data.The 2010 Rosetta developers meeting: macromolecular prediction and design meets reproducible publishing.
P2860
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P2860
Design, activity, and structure of a highly specific artificial endonuclease
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Design, activity, and structure of a highly specific artificial endonuclease
@ast
Design, activity, and structure of a highly specific artificial endonuclease
@en
Design, activity, and structure of a highly specific artificial endonuclease
@nl
type
label
Design, activity, and structure of a highly specific artificial endonuclease
@ast
Design, activity, and structure of a highly specific artificial endonuclease
@en
Design, activity, and structure of a highly specific artificial endonuclease
@nl
prefLabel
Design, activity, and structure of a highly specific artificial endonuclease
@ast
Design, activity, and structure of a highly specific artificial endonuclease
@en
Design, activity, and structure of a highly specific artificial endonuclease
@nl
P2093
P1433
P1476
Design, activity, and structure of a highly specific artificial endonuclease
@en
P2093
Barry L Stoddard
Brett S Chevalier
Meggen S Chadsey
Raymond J Monnat
P304
P356
10.1016/S1097-2765(02)00690-1
P407
P577
2002-10-01T00:00:00Z