Coevolution of a Homing Endonuclease and Its Host Target Sequence - Test2 - elhamkhani - TriplyDB

Coevolution of a Homing Endonuclease and Its Host Target Sequence

Coevolution of a Homing Endonuclease and Its Host Target Sequence

http://www.wikidata.org/entity/Q27647554

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Homing endonucleases: DNA scissors on a mission Recognition of a common rDNA target site in archaea and eukarya by analogous LAGLIDADG and His-Cys box homing endonucleases Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity Tapping natural reservoirs of homing endonucleases for targeted gene modification Activity, specificity and structure of I-Bth0305I: a representative of a new homing endonuclease family Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space LAHEDES: the LAGLIDADG homing endonuclease database and engineering server Motif-directed flexible backbone design of functional interactions.Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX)In vivo characterization of the homing endonuclease within the polB gene in the halophilic archaeon Haloferax volcanii.Mining endonuclease cleavage determinants in genomic sequence data.A synthetic homing endonuclease-based gene drive system in the human malaria mosquito Home and away- the evolutionary dynamics of homing endonucleases.Improved modeling of side-chain--base interactions and plasticity in protein--DNA interface design Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity The mitochondrial LSU rRNA group II intron of Ustilago maydis encodes an active homing endonuclease likely involved in intron mobility.Massively parallel determination and modeling of endonuclease substrate specificity Evolutionary maintenance of selfish homing endonuclease genes in the absence of horizontal transfer.Native homing endonucleases can target conserved genes in humans and in animal models.Evolutionary and biogeographical implications of degraded LAGLIDADG endonuclease functionality and group I intron occurrence in stony corals (Scleractinia) and mushroom corals (Corallimorpharia).The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.Analysis of the Mitochondrial Genome in Hypomyces aurantius Reveals a Novel Twintron Complex in Fungi.Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease.Impact of a homing intein on recombination frequency and organismal fitness.Assessment of the optimization of affinity and specificity at protein-DNA interfaces Exploitation of binding energy for catalysis and design.High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.Group I introns and inteins: disparate origins but convergent parasitic strategies.Reprogramming homing endonuclease specificity through computational design and directed evolution.Mobile DNA elements in T4 and related phages.Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification.Towards artificial metallonucleases for gene therapy: recent advances and new perspectives.Targeted gene therapies: tools, applications, optimization Bacterial group I introns: mobile RNA catalysts.Redox-responsive zinc finger fidelity switch in homing endonuclease and intron promiscuity in oxidative stress Social networking between mobile introns and their host genes.Restriction site free cloning (RSFC) plasmid family for seamless, sequence independent cloning in Pichia pastoris Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII.

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

http://www.wikidata.org/entity/Q27647554

description

2007 nî lūn-bûn

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2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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J.JMB.2007.07.052

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Journal of Molecular Biology

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Coevolution of a Homing Endonuclease and Its Host Target Sequence

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Audrey McConnell-Smith

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Barry L Stoddard

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Michelle Scalley-Kim

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P2860

Barriers to intron promiscuity in bacteria.

Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites

Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence

Design, activity, and structure of a highly specific artificial endonuclease

Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI

The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity

The structure of I-Crel, a group I intron-encoded homing endonuclease

DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI

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17720189

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