Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets
about
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbtHistone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factorsCrystal structure of the malignant brain tumor (MBT) repeats in Sex Comb on Midleg-like 2 (SCML2)Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midlegStructural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD FingerThe MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene RepressionSolution NMR Structure of the DNA-binding Domain from Scml2 (Sex Comb on Midleg-like 2)H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva developmentSolution structure of the PWWP domain of the hepatoma-derived growth factor familyHow chromatin-binding modules interpret histone modifications: lessons from professional pocket pickersStructure of the chromo barrel domain from the MOF acetyltransferase.Finding Inspiration in the Protein Data Bank to Chemically Antagonize Readers of the Histone Code.Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.Keeping it in the family: diverse histone recognition by conserved structural foldsChromatin reader L(3)mbt requires the Myb-MuvB/DREAM transcriptional regulatory complex for chromosomal recruitmentStructural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono- or dimethyllysine 20 on histone H4.L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure.The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.Intra-chain 3D segment swapping spawns the evolution of new multidomain protein architectures.A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repressionLIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes.Engineering of Methylation State Specific 3xMBT Domain Using ELISA Screening.Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer.MBT domain proteins in development and diseaseIdentification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.Chromatin in the nuclear landscape.Readout of epigenetic modifications.Mind the methyl: methyllysine binding proteins in epigenetic regulation.A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks.Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia veraA Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.
P2860
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P2860
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@ast
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@en
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@nl
type
label
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@ast
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@en
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@nl
prefLabel
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@ast
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@en
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@nl
P2093
P2860
P50
P3181
P1433
P1476
Malignant brain tumor repeats: ...... ligand/peptide binding pockets
@en
P2093
Piernicola Boccuni
Stephen D Nimer
Wooi Koon Wang
P2860
P304
P3181
P356
10.1016/S0969-2126(03)00127-8
P577
2003-07-01T00:00:00Z