Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation - Test2 - elhamkhani - TriplyDB

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

http://www.wikidata.org/entity/Q27643078

about

Biochemical profiling of histone binding selectivity of the yeast bromodomain family Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2 Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA Histone recognition and large-scale structural analysis of the human bromodomain family Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b The role of human bromodomains in chromatin biology and gene transcription Lysine acetylation: codified crosstalk with other posttranslational modifications Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 Combating the epigenome: epigenetic drugs against non-Hodgkin's lymphoma The bromodomain: from epigenome reader to druggable target Protein lysine acetylation by p300/CBP Acetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitro Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36 Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2 A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation Protein stability: a crystallographer's perspective p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3 Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo Multivalent engagement of chromatin modifications by linked binding modules Quantitative proteomic analysis of histone modifications Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails Thermodynamic analysis of acetylation-dependent Pb1 bromodomain-histone H3 interactions Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners.Anthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages.Acetylation goes global: the emergence of acetylation biology.Integration of small-molecule discovery in academic biomedical research Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells.Autoacetylation of the Ralstonia solanacearum effector PopP2 targets a lysine residue essential for RRS1-R-mediated immunity in Arabidopsis.

P2860

Q21142665-DC79EEE9-B494-4886-ACF6-F756AA104934 Q24295275-81A5B209-78F7-4106-B693-8E37FE613E48 Q24305108-9FC35620-397D-4DB6-8DCF-E778CB55AAC4 Q24310313-498A0476-C342-4EE1-8192-ED13FF4E8EA2 Q24310431-FACD6117-D0DA-4679-AEB5-3AA5FC0FFBBC Q24613876-565DBB4C-2570-438D-8DBA-1DF5FFAB244C Q24631840-B1C0E58B-6108-4834-BD80-41053BC4D21A Q24644959-C8BD888A-388E-4E8F-B9B0-760787EF9336 Q24681065-603E69A0-3032-494B-8E0A-3E677D215FBD Q26851166-145FA25F-CF1D-40C3-B696-C5ADF1CA4B60 Q26999935-3EE38176-FE32-40FB-962B-6119CC5D3CDE Q27021749-843FFC7A-1A62-4361-B6E9-41546929B2C8 Q27303150-9FCA90F9-8E9A-47A3-8516-E09C7B05BC28 Q27650290-260AEB43-2FFD-431F-B98A-0CDAD5F7E873 Q27652763-94204EC7-90C7-4E96-8628-81F9878E0CA3 Q27657784-0AED7E24-CC50-47C4-93F9-8592052D6D6B Q27658848-CFC607B9-B9A4-409C-965F-1AD4FA618BE4 Q27660428-576FDD42-FAD7-44E8-8069-CA014232589E Q27667526-2DF4B028-730E-493B-B8F6-D1EFBF90037A Q27681018-394C514F-2CF5-424C-BB67-66AD47A0990F Q27682105-0CACBAEB-7597-4D95-9AA6-33BD88428420 Q27685367-549584E9-F2D1-4803-BF2C-9046E6C1D0C3 Q28068775-15EF030B-34DF-40D4-BE8F-D1807E26961C Q28079390-B27E7659-7E87-4A30-8B47-F197871C5E69 Q28237121-8F7A2357-E13C-429E-9816-A1F566C9B5AB Q28242369-BDBA66B1-BC0C-40B7-AB5C-069BFD897A86 Q28256059-09DC6488-0841-4096-9096-BF2F408FAA7F Q28269627-3266737F-28B9-4253-B7F7-650D2A7FFF80 Q28507164-442AEAB9-621D-426E-A2A4-61A765B60E22 Q29617236-A59F5ED2-5D7F-410F-A3FB-622927007C2F Q30375585-95213A80-578D-4AF3-92CB-2F32080485A7 Q30570945-721EF234-F501-4785-AC52-35130A867961 Q33298555-CF1E7A7F-7B49-4C77-B7F8-EB739D7B46DB Q33314479-3D66984F-6EC6-4236-AA34-C6E7D7E126CC Q33325589-AF3202C5-4CBB-43DF-8292-FDCB86D50F53 Q33573969-20034F10-0FD8-4F05-9F14-013024FD8759 Q33616296-9F789E87-2CC7-4B34-B894-758D1CBD3DC3 Q33650024-4CE63745-410A-4216-A213-EF2B36DA61E7 Q33701358-F544192B-201C-4885-B2C4-70583865FA37 Q33761229-FF475399-078F-46D2-AC42-81A4C07E1548

P2860

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

http://www.wikidata.org/entity/Q27643078

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Structural mechanism of the br ...... p53 transcriptional activation

@ast

Structural mechanism of the br ...... p53 transcriptional activation

@en

Structural mechanism of the br ...... p53 transcriptional activation

@nl

type

label

Structural mechanism of the br ...... p53 transcriptional activation

@ast

Structural mechanism of the br ...... p53 transcriptional activation

@en

Structural mechanism of the br ...... p53 transcriptional activation

@nl

prefLabel

Structural mechanism of the br ...... p53 transcriptional activation

@ast

Structural mechanism of the br ...... p53 transcriptional activation

@en

Structural mechanism of the br ...... p53 transcriptional activation

@nl

P1433

Q27643078-C4A52F96-11E2-4BDE-91A9-D410620D556A

P1476

Q27643078-1057C80F-7E73-4669-A00C-CD114BB2C4E4

P2093

Q27643078-025A3F1E-1A03-41B8-8464-810811297657

Q27643078-086B29DC-106F-4231-9CF4-7B2E34F2EFCF

Q27643078-20AFB379-488E-468E-AD92-4C6B6356BA75

Q27643078-40EA4E1B-69AC-4797-AB5E-B6486E88873F

Q27643078-73924EB6-8CF5-47EB-8098-D11B3A1E9447

Q27643078-AC9FCE63-66F3-4D8A-B996-7D11A69963D2

Q27643078-D583B116-931C-4D09-B1B2-F54A2208C1ED

Q27643078-E38DEF44-1DBB-45E1-A43F-98C3590F6DCA

Q27643078-E49AA350-26CC-4F19-8F56-B975AE71E7C1

P304

Q27643078-DA697DB5-06C9-4783-A6E8-4741E5AE4C81

P31

Q27643078-D40F4F48-A058-4B1F-A616-D48191E7F26B

P3181

Q27643078-164FDDCF-1B5A-4C23-BE81-AC95C62B34EE

P356

Q27643078-6A16603C-B926-44A5-8561-4B475EEDF6AB

P433

Q27643078-EB8AB90E-F201-4A89-9EF5-D2B56EE41E36

P478

Q27643078-5A35E967-2EE7-4370-AF76-3FEF91506FF1

P50

Q27643078-4AC125DF-6942-4483-ACD9-C4CDCB587B97

P577

Q27643078-098CA0DF-EAE4-446A-98D5-69F2EA059C10

P698

Q27643078-D6CAFDAA-0262-4E98-913E-71A3589C71B4

P3181

P356

S1097-2765(03)00528-8

P1433

P1476

Structural mechanism of the br ...... p53 transcriptional activation

@en

P2093

Lei Zeng

http://www.w3.org/2001/XMLSchema#string

Ming-Ming Zhou

http://www.w3.org/2001/XMLSchema#string

Nancy J Zeleznik-Le

http://www.w3.org/2001/XMLSchema#string

Olga Plotnikova

http://www.w3.org/2001/XMLSchema#string

Roberto Sanchez

http://www.w3.org/2001/XMLSchema#string

Sachchidanand

http://www.w3.org/2001/XMLSchema#string

Sherry Yan

http://www.w3.org/2001/XMLSchema#string

Shiraz Mujtaba

http://www.w3.org/2001/XMLSchema#string

Yan He

http://www.w3.org/2001/XMLSchema#string

P304

251-63

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4829966

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/S1097-2765(03)00528-8

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P50

P577

2004-01-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

14759370

http://www.w3.org/2001/XMLSchema#string