Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin
about
Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate ComplexesInhibition of 1-Deoxy- d -Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic StudiesMolecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparumCrystal Structure of Brucella abortus Deoxyxylulose-5-phosphate Reductoisomerase-like (DRL) Enzyme Involved in Isoprenoid BiosynthesisAntimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate ReductoisomeraseKinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).Thermodynamic Investigation of Inhibitor Binding to 1-Deoxy-D-Xylulose-5-Phosphate ReductoisomeraseMolecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides.Mechanistic aspects of carotenoid biosynthesis.Convergent strategies in biosynthesis.Biochemistry of the non-mevalonate isoprenoid pathway.Crystallization and preliminary X-ray crystallographic study of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum.Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogensFrom Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis.Conformational dynamics of the flexible catalytic loop in Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.Biosynthesis of isoprenoids: studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase.NMR studies of DOXP reductoisomerase and its inhibitor complex.Inverse docking based screening and identification of protein targets for Cassiarin alkaloids against Plasmodium falciparum.The MEP pathway and the development of inhibitors as potential anti-infective agents
P2860
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P2860
Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@ast
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@en
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@nl
type
label
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@ast
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@en
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@nl
prefLabel
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@ast
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@en
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@nl
P2093
P2860
P921
P1476
Structure of 1-deoxy-D-xylulos ...... antimalarial drug fosmidomycin
@en
P2093
Daisuke Iino
Haruo Seto
Kanju Ohsawa
Kodai Hara
Shunsuke Yajima
Tomohisa Kuzuyama
Yasuyuki Sasaki
P2860
P304
P356
10.1107/S1744309107024475
P577
2007-06-01T00:00:00Z