Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78 - Test2 - elhamkhani - TriplyDB

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

http://www.wikidata.org/entity/Q27646351

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Turning the RING domain protein MdmX into an active ubiquitin-protein ligase SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine HECT and RING finger families of E3 ubiquitin ligases at a glance E2 enzymes: more than just middle men Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes Principles of allosteric interactions in cell signaling Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2 A Dual E3 Mechanism for Rub1 Ligation to Cdc53 E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6 Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin Conjugates Solution structure of lysine-free (K0) ubiquitin The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Cleaning up in the endoplasmic reticulum: ubiquitin in charge E2s: structurally economical and functionally replete An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125 Building ubiquitin chains: E2 enzymes at work The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.Molecular architecture and mechanism of the anaphase-promoting complex Efficient and generalized processing of multidimensional NUS NMR data: the NESTA algorithm and comparison of regularization terms.Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1.Structural and functional insights to ubiquitin-like protein conjugation.The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation Expanding the proteome: disordered and alternatively folded proteins.Twists and turns in ubiquitin-like protein conjugation cascades.Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance.The ubiquitination machinery of the ubiquitin system.Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade.

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P2860

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

http://www.wikidata.org/entity/Q27646351

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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Allosteric Activation of E2-RI ...... ific E2-Binding Region of gp78

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J.MOLCEL.2009.05.010

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Allosteric activation of E2-RI ...... ific E2-binding region of gp78

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Allan M Weissman

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Amanda S Altieri

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Jennifer Mariano

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Jess Li

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Ranabir Das

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Robert L McFeeters

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Sergey G Tarasov

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Zlatka Kostova

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P2860

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)

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674-685

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10.1016/J.MOLCEL.2009.05.010

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6

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34

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Ravi C Kalathur

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2009-06-01T00:00:00Z

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26324572

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